Misoprostol 100 mcg, 200 mcg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 100 mcg, 200 mcg

Reference Brands:

Category: Women's Health

Misoprostol is a medicine used for medical abortion (terminating a pregnancy). It is also used for preventing excessive bleeding after delivery. This medicine acts on the uterus and increases its contraction.

Product Description:

Misoprostol is a synthetic analogue of prostaglandin E1. It was developed to protect the stomach — prostaglandins maintain the gastric mucosal barrier, and NSAIDs deplete them — and it is still licensed in many countries for preventing NSAID-induced ulcers. Its effect on the uterus, originally an unwanted adverse effect, became its most important use: it causes cervical softening and uterine contraction, it is stable at room temperature, and it is inexpensive.

It appears on the WHO Model List of Essential Medicines for preventing and treating postpartum haemorrhage, for management of miscarriage and incomplete abortion, for cervical preparation before procedures, for labour induction, and, in combination with mifepristone, for medical abortion. Heat stability is what makes it valuable where oxytocin cannot be refrigerated. Uterine hyperstimulation and rupture are the serious risks, particularly at term or with a uterine scar. It is contraindicated in pregnancy when used for the gastric indication.

Sourcing notes. Legal status and registered indications differ sharply between countries, and in some markets only the gastric indication is registered. That position must be established before anything else. The tablets are highly moisture-sensitive, and degradation has been documented in poor packaging, so blister integrity and stability data for the destination climate zone matter.