Estradiol Valerate / Dienogest 1mg+2mg / 0.03mg+2mg Suppliers & Bulk Manufacturers
Available Forms: Tablet
Available Strengths: 1mg+2mg / 0.03mg+2mg
Reference Brands: Natazia (USA), Qlaira (EU), Valette(EU)
Category: Women's Health
Dienogest is a synthetic progestin used in hormonal contraceptives to prevent pregnancy. It works by inhibiting ovulation, thickening cervical mucus, and altering the endometrial lining to reduce the likelihood of implantation.
Product Description:
Estradiol valerate / Dienogest is a modern combined hormonal contraceptive designed to provide effective birth control while using an estrogen closer to the body’s natural hormone. Unlike many traditional contraceptives that contain ethinyl estradiol, this formulation uses estradiol valerate, which converts into 17β-estradiol in the body, a naturally occurring estrogen. The combination is typically supplied in a four-phase dosing regimen that gradually adjusts hormone levels throughout the cycle, including an estrogen step-down and progestin step-up approach, followed by a short two-day hormone-free interval.
Dienogest, the progestin component, is derived from 19-nortestosterone and has strong progestational activity on the endometrium. It is also known for its antiandrogenic properties, which may help improve tolerability in some women. Together, estradiol valerate and dienogest work to prevent ovulation, stabilize the uterine lining, and create hormonal conditions that reduce the chance of pregnancy.
This combination has been shown to provide reliable contraception and is also used in the management of heavy menstrual bleeding in women who prefer oral contraception. Clinical data suggest that its metabolic effects and safety profile are generally comparable to those observed with many established contraceptives.
Estradiol Valerate / Dienogest — third party manufacturing & bulk supply
Estradiol Valerate / Dienogest 1mg+2mg / 0.03mg+2mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Estradiol Valerate / Dienogest is supplied as Tablet — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Estradiol Valerate / Dienogest listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Estradiol Valerate / Dienogest →Frequently Asked Questions
This medicine is used for contraception (birth control) in women. It is also prescribed to treat heavy menstrual bleeding in women who choose oral contraception as a method of birth control. The combination works by preventing ovulation, altering the uterine lining, and thickening cervical mucus to reduce the chance of pregnancy.
The medicine contains two active ingredients: estradiol valerate, an estrogen hormone that converts to estradiol in the body, and dienogest, a progestin that helps regulate hormonal balance and supports contraceptive action.
Common trade names include Qlaira and Natazia marketed in different regions such as Europe, the United States, and other global markets.
These products are developed and marketed by Bayer for use in multiple international markets.
The generic names are estradiol valerate and dienogest.
Brand names include Qlaira and Natazia.
Estradiol valerate / Dienogest products are manufactured in pharmaceutical facilities in Europe and other regulated markets that supply hormonal contraceptives globally under approved regulatory standards.
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