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Alprazolam / Propranolol Tablet bulk supplier for pharma manufacturers

Alprazolam / Propranolol Tablet 0.25mg + 20mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 0.25mg + 20mg

Reference Brands: -

Category: Antipsychotropic Drugs

Alprazolam + propranolol tablets (0.25 mg + 20 mg) combine a benzodiazepine with a beta-blocker for anxiety with physical symptoms such as palpitations and tremor. The combination is marketed in India, not in the US or EU. It is a controlled medicine in most countries, so we check the buyer's import permits before quoting.

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Product Description:

A 6-week double-blind, controlled clinical study was conducted to evaluate the efficacy of propranolol hydrochloride and alprazolam in patients diagnosed with agoraphobia with panic disorder or panic disorder with or without limited phobic avoidance. The study included 29 patients, where 14 patients received alprazolam at a mean daily dose of 5.0 ± 2.3 mg, while 15 patients were treated with propranolol at a mean daily dose of 182.0 ± 60.5 mg.

The findings demonstrated that both alprazolam and propranolol were effective in suppressing panic attacks and reducing avoidance behavior associated with these conditions. Alprazolam, a benzodiazepine, showed a more rapid onset of its panicolytic effect, providing quicker symptomatic relief. Propranolol, a non-selective beta-blocker, also contributed to the management of physical symptoms related to anxiety and panic, such as palpitations and tremors.

Although alprazolam demonstrated faster action, propranolol showed promising results and may serve as a useful therapeutic option, particularly in patients where control of somatic symptoms is required. The study suggests that propranolol warrants further clinical evaluation to better define its role in the treatment of panic-related disorders.

Controlled medicine — licensed supply only

This product is controlled in many countries under narcotic, psychotropic, precursor or other drug laws, which vary by country. We supply only licensed buyers holding any import certificate, permit or authorisation their national authority requires, and the Indian manufacturer or exporter must hold the required licences. In India, each export of a narcotic drug or psychotropic substance needs an export authorisation, and export of ephedrine, pseudoephedrine or their preparations a No Objection Certificate, from the Narcotics Commissioner (Central Bureau of Narcotics). We verify permits before quoting.

Alprazolam / Propranolol Tablet — third party manufacturing & bulk supply

Alprazolam / Propranolol Tablet 0.25mg + 20mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Alprazolam / Propranolol Tablet is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Alprazolam / Propranolol Tablet listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

This combination is used for the management of anxiety disorders, especially where physical symptoms such as palpitations, tremors, and increased heart rate are present. It is also used in conditions like performance anxiety, stress-related hypertension, and anxiety associated with cardiovascular symptoms.

It is made from alprazolam, which enhances GABA activity in the brain to produce a calming effect, and propranolol hydrochloride, a beta-blocker that reduces physical symptoms of anxiety by controlling heart rate and blood pressure.

Common trade names include Trika Beta, Anxit Beta, Alprax Beta, Restyl Beta, and several other region-specific branded generics.

More than one company makes it, including manufacturers in India. Share your market and we will find licensed makers whose documents fit.

The generic names are alprazolam and propranolol hydrochloride.

Brand names include Trika Beta, Anxit Beta, Alprax Beta, Restyl Beta, and other local branded generics.

It is primarily manufactured in India and exported to various regions including Asia, Africa, and LATAM markets, with limited availability in regulated markets like the USA and EU as a fixed-dose combination.

Doctors in India for anxiety with physical symptoms such as palpitations and tremor, usually short-term.

Benzodiazepine dependence, and beta-blocker cautions in asthma, heart block and diabetes.

Alprazolam is a Schedule IV substance, so import and export permits are required, in addition to registration of this combination in the destination.

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