Alprazolam / Sertraline Tablet bulk supplier for pharma manufacturers

Alprazolam / Sertraline Tablet 0.25mg + 25mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 0.25mg + 25mg

Reference Brands: Various Indian Brand Available

Alprazolam + Sertraline is a combination of two medicines: Alprazolam and Sertraline, which has anxiety-lowering and mood-enhancing effects. Alprazolam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Sertraline is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood.

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Product Description:

A 12-week, placebo-controlled outpatient study was conducted to evaluate the efficacy and safety of sertraline hydrochloride and alprazolam in patients diagnosed with panic disorder, with and without agoraphobia, according to ICD-10 criteria. The study included 40 adult patients aged 18 years and above, who were randomly assigned to receive either sertraline or alprazolam in fixed doses.

Sertraline was administered at a dose of 20 mg per day, while alprazolam was given in doses ranging from 1 to 1.5 mg per day. The evaluation focused on key clinical parameters, including the frequency of panic attacks, severity of agoraphobia, and levels of anticipatory anxiety.

The results demonstrated that both sertraline and alprazolam significantly reduced the frequency of panic attacks in patients with panic disorder. In addition, notable improvements were observed in symptoms of agoraphobia and anticipatory anxiety. These findings highlight the effectiveness of both medications in managing panic disorder, with each offering therapeutic benefits in reducing acute anxiety symptoms and improving overall patient outcomes when used under appropriate medical supervision.

Alprazolam / Sertraline Tablet — third party manufacturing & bulk supply

Alprazolam / Sertraline Tablet 0.25mg + 25mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Alprazolam / Sertraline Tablet is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Alprazolam / Sertraline Tablet listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

This combination is used for the treatment of anxiety disorders associated with depression, panic disorders, and mixed anxiety-depressive conditions. It helps provide rapid relief from anxiety symptoms while also addressing underlying depression.

It is made from alprazolam, a benzodiazepine that enhances GABA activity to produce a calming effect, and sertraline hydrochloride, an SSRI that increases serotonin levels in the brain to improve mood and emotional balance.

Common trade names include Alprasafe Plus, Restyl Plus, Serlift Plus, Alprazolam + Sertraline Tablets (generic labeling), and other region-specific branded generics.

This combination is manufactured by multiple pharmaceutical companies, especially in India and emerging markets, including companies like Sun Pharma, Cipla, Intas, and others.

The generic names are alprazolam and sertraline hydrochloride.

Brand names include Alprasafe Plus, Restyl Plus, Serlift Plus, and other local branded generics.

It is primarily manufactured in India and supplied to various regions including Asia, Africa, and LATAM markets, with limited availability in regulated markets like the USA and EU as a fixed-dose combination.