Mecamylamine Hydrochloride 2.5 mg, 5 mg,10 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 2.5 mg, 5 mg,10 mg

Reference Brands: Vecamyl (USA/EU)

Category: Neurology

Mecamylamine Hydrochloride is a Neurology product available as Tablets in strengths 2.5 mg, 5 mg,10 mg. It corresponds to the reference brand Vecamyl (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Mecamylamine is a non-selective, non-competitive antagonist at nicotinic acetylcholine receptors, and unlike the quaternary ganglionic blockers it is a secondary amine that crosses the blood-brain barrier. It was introduced as an oral antihypertensive at a time when ganglionic blockade was one of the few options available, and was made obsolete for that purpose by every subsequent class — the postural hypotension, constipation, urinary retention and blurred vision that follow from blocking autonomic ganglia indiscriminately are not tolerable when alternatives exist.

Its continuing interest is central. Because it reaches the brain and blocks neuronal nicotinic receptors, it has been investigated in smoking cessation, Tourette syndrome and depression, and it remains a reference pharmacological tool for nicotinic receptor blockade in research settings.

Sourcing notes. Off patent but discontinued or never registered in most markets, with very few manufacturers. Confirm registrability in the destination market as the first step — assuming availability from the fact that someone manufactures it is the usual error here. Enquiries are as likely to be research or specialist compounding as conventional pharmaceutical supply, which changes the documentation expected.