Carbidopa 25 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 25 mg
Reference Brands: Generic formulations marketed under different names
Category: Neurology
Carbidopa is a Neurology product available as Tablets in strengths 25 mg. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Carbidopa, marketed under the brand name Lodosyn, is a medication primarily used in the management of Parkinson’s disease. It works by inhibiting the enzyme aromatic L-amino-acid decarboxylase (DOPA decarboxylase or DDC) in the peripheral tissues, which prevents the premature conversion of Levodopa to dopamine outside the brain. This inhibition allows a greater proportion of administered Levodopa to cross the blood–brain barrier and exert its therapeutic effect in the central nervous system, effectively improving the control of Parkinson’s disease symptoms such as tremor, rigidity, and bradykinesia.
By selectively targeting peripheral DDC, Carbidopa enhances the bioavailability of Levodopa while minimizing side effects related to peripheral dopamine accumulation, including nausea, vomiting, and cardiovascular issues. The medication is available in oral tablet form and is often used in combination with Levodopa for optimal therapeutic outcomes. Carbidopa’s ability to preserve Levodopa for central nervous system activity makes it an essential component in Parkinson’s disease therapy, supporting both motor function and quality of life for patients. Its predictable pharmacologic profile and compatibility with Levodopa make it a preferred agent in long-term Parkinson’s disease management.
Carbidopa — third party manufacturing & bulk supply
Carbidopa 25 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Carbidopa listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Carbidopa →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Carbidopa is used in the treatment of Parkinson’s disease and other movement disorders. It is administered alongside Levodopa to prevent the peripheral conversion of Levodopa to dopamine, increasing its availability in the brain and improving control of symptoms such as tremor, rigidity, and bradykinesia.
Carbidopa is a synthetic compound that acts as a dopa-decarboxylase inhibitor. It is chemically designed to inhibit the peripheral metabolism of Levodopa without crossing the blood-brain barrier.
Carbidopa is marketed under several trade names, the most widely recognized being Sinemet. Other brand names include Parcopa and Atamet.
Sinemet (Carbidopa/Levodopa) is manufactured by Merck & Co. in the USA. Other generic and brand versions are produced by multiple pharmaceutical companies worldwide, depending on the market.
The generic name is Carbidopa.
The brand names include Sinemet, Parcopa, and Atamet.
Carbidopa is manufactured in GMP-approved facilities in the USA, Europe, and other regulated markets, depending on the brand or generic manufacturer.
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