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Dichlorphenamide bulk supplier for pharma manufacturers

Dichlorphenamide 50 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 50 mg

Reference Brands: Keveyis (USA/EU)

Category: Neurology

Dichlorphenamide is a Neurology product available as Tablets in strengths 50 mg. It corresponds to the reference brand Keveyis (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Dichlorphenamide, also known as diclofenamide, is a sulfonamide-based carbonic anhydrase inhibitor belonging to the meta-disulfamoylbenzene class. It is classified as a first-generation carbonic anhydrase inhibitor and has a long history of clinical use across multiple therapeutic areas. The drug works by inhibiting carbonic anhydrase enzymes, leading to alterations in electrolyte balance and cellular excitability.

Historically, dichlorphenamide was approved in the United States in 1958 under the brand name Daranide for the treatment of glaucoma, including acute angle-closure glaucoma. Over time, it was also found to be effective in certain cases of therapy-resistant epilepsy. Further clinical research later established its role in neuromuscular disorders.

In 2015, dichlorphenamide received approval in the United States as an orphan drug under the brand name Keveyis for the treatment of primary periodic paralysis, including both hypokalemic and hyperkalemic forms. By stabilizing muscle membrane excitability, it helps reduce the frequency and severity of paralytic attacks. Due to its pharmacological activity, dichlorphenamide is prescribed under specialist supervision with appropriate clinical monitoring.

Dichlorphenamide — third party manufacturing & bulk supply

Dichlorphenamide 50 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Dichlorphenamide listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Dichlorphenamide is used for the treatment of primary periodic paralysis, including hyperkalemic periodic paralysis, hypokalemic periodic paralysis, and related variants, in adult and pediatric patients.

Dichlorphenamide is a synthetic small-molecule carbonic anhydrase inhibitor formulated for oral administration.

The trade name of dichlorphenamide is Keveyis.

Keveyis is developed and marketed by Strongbridge Biopharma, which is now part of Xeris Biopharma.

The complete generic name is dichlorphenamide.

The approved brand name is Keveyis.

Dichlorphenamide is manufactured in GMP-approved facilities in the USA and other regulated pharmaceutical manufacturing regions, depending on the authorized manufacturer and supply chain.

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