Tolcapone 100 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 100 mg
Reference Brands: Tasmar (USA/EU)
Category: Neurology
Tolcapone is a Neurology product available as Tablets in strengths 100 mg. It corresponds to the reference brand Tasmar (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Tolcapone is a prescription medicine used in the management of Parkinson’s disease and is commonly marketed under the brand name Tasmar. It belongs to a class of drugs known as catechol-O-methyltransferase (COMT) inhibitors. Tolcapone works by blocking the COMT enzyme, which is responsible for breaking down levodopa in the body. By inhibiting this enzyme, tolcapone increases and prolongs the effect of levodopa, helping to improve motor symptoms such as stiffness, tremor, and slowness of movement in patients receiving levodopa/carbidopa therapy. It is considered a selective, potent, and reversible nitrocatechol-type COMT inhibitor.
Due to its mechanism and strong effect, tolcapone is typically used as an add-on treatment when standard Parkinson’s therapy does not provide sufficient symptom control. However, its clinical use is limited because it has been associated with serious liver toxicity. For this reason, strict liver function monitoring is required during treatment, and marketing authorization has been suspended or restricted in several countries. As a result, tolcapone is generally reserved for carefully selected patients under close medical supervision.
Tolcapone — third party manufacturing & bulk supply
Tolcapone 100 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Tolcapone listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Tolcapone →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Tolcapone is used as an adjunct treatment for Parkinson’s disease in patients taking levodopa/carbidopa who experience wearing-off symptoms and inadequate response to standard therapy.
Tolcapone is a synthetic small-molecule catechol-O-methyltransferase (COMT) inhibitor chemically designed to block peripheral and central COMT enzyme activity.
The main trade name of tolcapone is Tasmar.
Tasmar was originally developed and marketed by Roche (Genentech/Hoffmann-La Roche), with generics manufactured by multiple companies in different regions.
The generic name is tolcapone.
The brand name is Tasmar.
Tolcapone tablets are manufactured by various GMP-certified pharmaceutical manufacturers globally, depending on the brand or generic supplier.
Related Products
Valproic Acid
Strength:
125 mg/mL, 200 mg, 250 mg, 300 mg, 500 mg, 100 mg/mL
Form: Tablet / Capsule/ Injection / Oral syrup
Reference Brands: Depakene (USA), Depakine (EU/LATAM), Valprol (India)
View Details
Ropinirole Hydrochloride
Strength:
0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg
Form: Tablets
Reference Brands: Requip (USA)
View DetailsQuick Response Guaranteed | Verified Suppliers
