L-Methylfolate, Cyanocobalamin, Pyridoxal 5 Phosphate, Biotin Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: -

Reference Brands:

Category: Nutraceuticals

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Product Description:

This tablet combines active forms of B vitamins: L-methylfolate, the biologically active form of folate; pyridoxal 5'-phosphate, the active form of vitamin B6; cyanocobalamin, vitamin B12; and biotin. L-methylfolate does not need conversion by the MTHFR enzyme, so it is marketed for people with common variants of that gene. Together, folate, B6 and B12 lower homocysteine and are needed for red blood cell formation and nervous system function.

Such combinations are used for deficiency, in pregnancy planning, and alongside treatment for raised homocysteine. Whether MTHFR variants justify methylfolate rather than folic acid is debated; folic acid remains the form proven to prevent neural tube defects. High-dose folate can mask the anaemia of B12 deficiency while nerve damage progresses, which is why B12 is included. Biotin interferes with many laboratory immunoassays, including thyroid and cardiac tests, so patients should mention it before blood tests.

Sourcing notes. Buyers should specify the dose of each component when enquiring. Stabilised L-methylfolate salts are protected by patents and trademarks from a few suppliers, so the source and licence matter. Pyridoxal 5'-phosphate is less stable than pyridoxine. Folate and B6 content must fit the destination market's supplement limits.