Myo-Inositol, D- Chiro Ionositol, L-Methylfolate, Vitamin D3, Pyridoxil 5 Phosphate Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: -

Reference Brands:

Category: Nutraceuticals

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Product Description:

This tablet combines myo-inositol and D-chiro-inositol with L-methylfolate, vitamin D3 and pyridoxal 5'-phosphate. Myo-inositol and D-chiro-inositol are forms of inositol that act as second messengers in insulin signalling; in the ovary, myo-inositol mediates the effect of follicle-stimulating hormone. The combination is marketed for polycystic ovary syndrome, where insulin resistance is common. Folate, vitamin D and B6 are added for general and preconception support.

Small trials report that inositol improves insulin sensitivity and ovulation in some women with PCOS, and a ratio of about 40:1 myo- to D-chiro-inositol, mirroring plasma levels, is often promoted. The evidence is of low to moderate quality, and international PCOS guidelines regard inositol as experimental. Lifestyle measures and established treatments come first. High doses of D-chiro-inositol alone may impair oocyte quality. The product is generally well tolerated, with occasional mild digestive upset.

Sourcing notes. Buyers should specify the dose of each component and the inositol ratio when enquiring. Stabilised L-methylfolate salts are proprietary. Inositol is needed in gram quantities, so a tablet may not deliver an evidence-based dose; buyers should confirm the per-dose amount against published regimens. PCOS and fertility claims are restricted.