Glasdegib Maleate 25 mg, 100 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 25 mg, 100 mg
Reference Brands: Daurismo (USA/EU)
Category: Oncology Cancer Care
Glasdegib Maleate is a Oncology Cancer Care product available as Tablets in strengths 25 mg, 100 mg. It corresponds to the reference brand Daurismo (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Glasdegib maleate is an orally administered small-molecule anticancer agent used primarily in the treatment of newly diagnosed acute myeloid leukemia (AML). It is indicated for use in combination with low-dose cytarabine in adult patients who are 75 years of age or older, or in patients who are not suitable candidates for intensive chemotherapy due to comorbidities or overall health status. Glasdegib maleate is also being studied for its potential role in the treatment of other malignancies.
Glasdegib maleate is the maleate salt form of glasdegib and functions as a selective inhibitor of the Smoothened (SMO) receptor, a key component of the Hedgehog (Hh) signaling pathway. Upon oral administration, the drug binds to and inhibits SMO, leading to suppression of aberrant Hedgehog pathway activation. This pathway plays a critical role in cellular growth, differentiation, tissue repair, and the survival of cancer stem cells.
Constitutive activation of the Hedgehog signaling pathway has been observed in various cancers and is associated with uncontrolled tumor cell proliferation. By blocking this pathway, glasdegib maleate helps inhibit tumor growth and supports disease control in Hedgehog-dependent malignancies.
Glasdegib Maleate — third party manufacturing & bulk supply
Glasdegib Maleate 25 mg, 100 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Glasdegib Maleate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Glasdegib Maleate →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Glasdegib maleate is used in the treatment of acute myeloid leukemia (AML). It is indicated for adult patients who are newly diagnosed with AML and are not eligible for intensive induction chemotherapy. It is commonly used in combination with low-dose cytarabine to help inhibit cancer cell growth and disease progression.
Glasdegib maleate is a small-molecule synthetic compound formulated as the maleate salt of glasdegib. It functions as a selective inhibitor of the Smoothened (SMO) receptor within the Hedgehog signaling pathway.
The trade name of glasdegib maleate is Daurismo.
Glasdegib maleate is manufactured and marketed by Pfizer Inc.
The generic name of the drug is glasdegib maleate.
The brand name of glasdegib maleate is Daurismo.
Glasdegib maleate is manufactured under Pfizer’s global pharmaceutical manufacturing network in accordance with international regulatory standards.
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