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Trilaciclib Dihydrochloride bulk supplier for pharma manufacturers

Trilaciclib Dihydrochloride 300 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 300 mg

Reference Brands: Cosela (USA)

Category: Oncology Cancer Care

Trilaciclib Dihydrochloride is a Oncology Cancer Care product available as Injection in strengths 300 mg. It corresponds to the reference brand Cosela (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Trilaciclib, marketed under the brand name Cosela, is a first-in-class CDK4/6 inhibitor designed to reduce the frequency of chemotherapy-induced bone marrow suppression in adults. It is indicated for patients receiving specific chemotherapy regimens for extensive-stage small cell lung cancer (SCLC). By inhibiting cyclin-dependent kinase 4/6, trilaciclib temporarily arrests hematopoietic stem and progenitor cells in the G1 phase of the cell cycle, thereby protecting bone marrow from chemotherapy-induced damage.

Trilaciclib is administered intravenously prior to chemotherapy under medical supervision and is intended to preserve bone marrow function without compromising the anticancer activity of chemotherapeutic agents. Its protective mechanism helps reduce the incidence of myelosuppression, including neutropenia, anemia, and thrombocytopenia, which can improve patient outcomes and allow for the continuation of scheduled chemotherapy cycles.

Trilaciclib Dihydrochloride — third party manufacturing & bulk supply

Trilaciclib Dihydrochloride 300 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Trilaciclib Dihydrochloride listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions


Trilaciclib dihydrochloride is used to protect bone marrow cells during chemotherapy by reducing the incidence of chemotherapy-induced myelosuppression, including neutropenia, anemia, and thrombocytopenia, without affecting the anticancer activity of chemotherapeutic agents.


Trilaciclib dihydrochloride is a synthetic CDK4/6 inhibitor that temporarily arrests hematopoietic stem and progenitor cells in the G1 phase of the cell cycle to protect them from chemotherapy-induced damage.


Trilaciclib dihydrochloride is marketed under the trade name Cosela.


Trilaciclib dihydrochloride (Cosela) is manufactured by G1 Therapeutics, Inc., with production depending on regional regulatory approvals.


The generic name of the product is trilaciclib dihydrochloride.


A commonly recognized brand name of trilaciclib dihydrochloride is Cosela.


Trilaciclib dihydrochloride is manufactured in countries including the USA and EU regions, depending on the approved manufacturer and market authorization.

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