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Trilaciclib Dihydrochloride bulk supplier for pharma manufacturers

Trilaciclib Dihydrochloride Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 300 mg

Reference Brands: Cosela (USA)

Category: Oncology Cancer Care

Trilaciclib Dihydrochloride is available in Injection and strengths such as 300 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Trilaciclib Dihydrochloride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Trilaciclib Dihydrochloride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Trilaciclib, marketed under the brand name Cosela, is a first-in-class CDK4/6 inhibitor designed to reduce the frequency of chemotherapy-induced bone marrow suppression in adults. It is indicated for patients receiving specific chemotherapy regimens for extensive-stage small cell lung cancer (SCLC). By inhibiting cyclin-dependent kinase 4/6, trilaciclib temporarily arrests hematopoietic stem and progenitor cells in the G1 phase of the cell cycle, thereby protecting bone marrow from chemotherapy-induced damage.

Trilaciclib is administered intravenously prior to chemotherapy under medical supervision and is intended to preserve bone marrow function without compromising the anticancer activity of chemotherapeutic agents. Its protective mechanism helps reduce the incidence of myelosuppression, including neutropenia, anemia, and thrombocytopenia, which can improve patient outcomes and allow for the continuation of scheduled chemotherapy cycles.

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Frequently Asked Questions


Trilaciclib dihydrochloride is used to protect bone marrow cells during chemotherapy by reducing the incidence of chemotherapy-induced myelosuppression, including neutropenia, anemia, and thrombocytopenia, without affecting the anticancer activity of chemotherapeutic agents.


Trilaciclib dihydrochloride is a synthetic CDK4/6 inhibitor that temporarily arrests hematopoietic stem and progenitor cells in the G1 phase of the cell cycle to protect them from chemotherapy-induced damage.


Trilaciclib dihydrochloride is marketed under the trade name Cosela.


Trilaciclib dihydrochloride (Cosela) is manufactured by G1 Therapeutics, Inc., with production depending on regional regulatory approvals.


The generic name of the product is trilaciclib dihydrochloride.


A commonly recognized brand name of trilaciclib dihydrochloride is Cosela.


Trilaciclib dihydrochloride is manufactured in countries including the USA and EU regions, depending on the approved manufacturer and market authorization.

Yes, Trilaciclib Dihydrochloride is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Trilaciclib Dihydrochloride is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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