Bedaquiline Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 100 mg

Reference Brands: Sirturo (USA/EU)

Category: Antibiotics

Bedaquiline is available in Tablets and strengths such as 100 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Bedaquiline is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Bedaquiline can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

Product Description:

Bedaquiline, also known as BDQ and marketed under the brand name Sirturo, is an oral antibiotic used for the treatment of active tuberculosis, specifically multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). It is used in combination with other anti-tuberculosis medications to enhance treatment efficacy and reduce the bacterial load in patients with resistant forms of TB.

Approved by the U.S. Food and Drug Administration in December 2012 under a fast-track accelerated approval program, Bedaquiline provides a critical option for cases where conventional therapies are ineffective or not tolerated. As a diarylquinoline-class antibiotic, it works by selectively inhibiting mycobacterial ATP synthase, an enzyme essential for energy production in Mycobacterium tuberculosis, thereby killing the bacteria.

Bedaquiline is available as oral tablets, typically in 100 mg strength, and is administered as part of a carefully monitored treatment regimen due to potential cardiac and hepatic side effects. Its introduction has significantly improved outcomes in patients with drug-resistant tuberculosis, offering a novel mechanism of action that complements standard TB therapies.