Bedaquiline 100 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 100 mg

Reference Brands: Sirturo (USA/EU)

Category: Antibiotics

Bedaquiline is a Antibiotics product available as Tablets in strengths 100 mg. It corresponds to the reference brand Sirturo (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Bedaquiline, also known as BDQ and marketed under the brand name Sirturo, is an oral antibiotic used for the treatment of active tuberculosis, specifically multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). It is used in combination with other anti-tuberculosis medications to enhance treatment efficacy and reduce the bacterial load in patients with resistant forms of TB.

Approved by the U.S. Food and Drug Administration in December 2012 under a fast-track accelerated approval program, Bedaquiline provides a critical option for cases where conventional therapies are ineffective or not tolerated. As a diarylquinoline-class antibiotic, it works by selectively inhibiting mycobacterial ATP synthase, an enzyme essential for energy production in Mycobacterium tuberculosis, thereby killing the bacteria.

Bedaquiline is available as oral tablets, typically in 100 mg strength, and is administered as part of a carefully monitored treatment regimen due to potential cardiac and hepatic side effects. Its introduction has significantly improved outcomes in patients with drug-resistant tuberculosis, offering a novel mechanism of action that complements standard TB therapies.