Rifampin Suppliers & Bulk Manufacturers

Available Forms: Capsule / Oral suspension

Available Strengths: 150 mg, 300 mg, 50 mg/5 mL, 100 mg/5 mL

Reference Brands: Rifadin (USA), Rimactane (USA)

Category: Antibiotics

Rifampin is a Antibiotics product available as Capsule / Oral suspension in strengths 150 mg, 300 mg, 50 mg/5 mL, 100 mg/5 mL. It corresponds to the reference brands Rifadin (USA), Rimactane (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Rifampin, also known as rifampicin, is a broad-spectrum antibiotic widely used in the treatment of mycobacterial and certain gram-positive and gram-negative bacterial infections. It is a cornerstone therapy for tuberculosis, leprosy, and infections caused by methicillin-resistant Staphylococcus aureus (MRSA), as well as for prophylaxis against Neisseria meningitidis.

Rifampin exerts its bactericidal activity by selectively inhibiting bacterial DNA-dependent RNA polymerase (RNAP), which halts RNA synthesis and prevents bacterial replication. This occurs either by sterically blocking the elongating RNA at its 5′ end or by decreasing RNAP’s affinity for short RNA transcripts, effectively stopping microbial transcription without affecting human RNAP. Its mechanism makes it a powerful and essential drug for combating resistant and difficult-to-treat infections.

Available in oral capsules, tablets, and intravenous formulations, rifampin is often administered in combination with other antimicrobial agents to prevent resistance development. While generally well-tolerated, patients require monitoring for potential adverse effects, including hepatotoxicity, gastrointestinal disturbances, and interactions with other medications. Its broad-spectrum efficacy, targeted mechanism, and essential role in combination therapies make rifampin a critical agent in the management of serious bacterial and mycobacterial infections.