Omaveloxolone Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 150 mg

Reference Brands: Skyclarys (USA)

Category: Antibiotics

Omaveloxolone is available in Tablets and strengths such as 150 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Omaveloxolone is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Omaveloxolone can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

Product Description:

Omaveloxolone, marketed under the brand name Skyclarys, is an oral medication approved for the treatment of Friedreich’s ataxia, a rare and progressive neurodegenerative disorder. Friedreich’s ataxia causes damage to the spinal cord, peripheral nerves, and brain, leading to uncoordinated muscle movements, poor balance, difficulty walking, and changes in speech and swallowing. The disease often develops in childhood or adolescence and can progressively worsen over time, sometimes also affecting cardiac function and reducing life expectancy.

Omaveloxolone works by activating the Nrf2 pathway, a key regulator of cellular antioxidant defense. This mechanism helps reduce oxidative stress and improves mitochondrial function, which can slow disease progression and support neurological function. Taken orally, Omaveloxolone provides a convenient option for long-term management, aiming to improve patients’ mobility, balance, and overall quality of life. As an orphan drug, it offers a targeted therapeutic option for patients with this rare condition, addressing a significant unmet medical need.