Rifaximin 100 mg/5 mL, 200 mg, 550 mg Suppliers & Bulk Manufacturers
Available Forms: Tablet / Oral Suspension
Available Strengths: 100 mg/5 mL, 200 mg, 550 mg
Reference Brands: Xifaxan (USA), Targaxan (EU), Normix (LATAM)
Category: Antibiotics
Rifaximin is an antibiotic that acts almost entirely inside the gut, used for traveller's diarrhoea, to prevent hepatic encephalopathy and for IBS with diarrhoea. Tablets come in 200 mg and 550 mg. It is sold as Xifaxan (US), Targaxan (UK) and Normix; generic versions are marketed in India and other markets, while US patents still apply. Patent status differs by country, so we confirm what can lawfully be supplied to your destination before quoting.
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Product Description:
Rifaximin is a semi-synthetic rifamycin that inhibits bacterial DNA-dependent RNA polymerase. What distinguishes it from the rest of the class is pharmacokinetic rather than microbiological: oral absorption is under one per cent, so it acts almost entirely within the gut lumen and produces essentially no systemic exposure. That is the basis of both its safety profile and its indications.
Use is strength-dependent. The 200 mg strength treats travellers' diarrhoea caused by non-invasive Escherichia coli. The 550 mg strength is used to reduce recurrence of overt hepatic encephalopathy, where it lowers ammonia-producing gut flora, and for irritable bowel syndrome with diarrhoea. Because systemic absorption is minimal, the usual rifamycin concerns about hepatic enzyme induction and drug interactions largely do not apply.
Sourcing notes. The critical issue here is polymorphism, and it catches buyers out. Rifaximin exists in multiple crystalline forms with different solubility, and because solubility governs how much is absorbed, the polymorph affects both efficacy in the gut and systemic exposure. Polymorph identity has been the subject of extensive patent litigation, so a supplier's form determines freedom to operate as much as it determines performance. Require the polymorphic form to be specified and characterised, with supporting XRPD data, before treating any two offers as comparable.
Rifaximin — third party manufacturing & bulk supply
Rifaximin 100 mg/5 mL, 200 mg, 550 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Rifaximin is supplied as Tablet / Oral Suspension — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Rifaximin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Rifaximin →Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.
Frequently Asked Questions
Rifaximin is used to treat certain bacterial infections of the gastrointestinal tract. It is commonly prescribed for traveler’s diarrhea caused by noninvasive strains of Escherichia coli, hepatic encephalopathy to reduce the risk of recurrence, and irritable bowel syndrome with diarrhea (IBS-D). Because it acts mainly in the intestines and is minimally absorbed into the bloodstream, it targets bacteria in the gut.
Rifaximin is a semisynthetic derivative of rifamycin, an antibiotic compound originally derived from Streptomyces bacteria. The active pharmaceutical ingredient is formulated into oral tablets or suspensions designed to act locally in the gastrointestinal tract.
Common trade names of rifaximin include Xifaxan, Targaxan, Normix, Rifagut, and several other regional branded generics marketed in different countries.
Rifaximin products such as Xifaxan are marketed by companies including Salix Pharmaceuticals (a subsidiary of Bausch Health Companies), while Normix is associated with Alfasigma and various generic manufacturers worldwide.
The generic name is rifaximin.
Brand names include Xifaxan, Targaxan, Normix, Rifagut, and other country-specific rifaximin brands.
Rifaximin is manufactured in multiple countries including the United States, Italy, India, and other global pharmaceutical manufacturing hubs where companies produce the medicine under GMP-compliant facilities for international markets.
200 mg three times daily for traveller's diarrhoea, 550 mg twice daily to prevent hepatic encephalopathy, and 550 mg three times daily for 14 days for IBS-D.
Yes, in India and many other markets. In the US, Xifaxan patents and litigation delay generic entry.
200 mg and 550 mg tablets and granules for oral suspension (in some markets).
Rifaximin was developed in Italy by Alfa Wassermann, now part of Alfasigma, which sells it under brands such as Normix. In the United States it is sold as Xifaxan by Salix, part of Bausch Health, and in the UK as Targaxan by Norgine. Xifaxan is a trademark of Salix; PharmaTradz is not affiliated with or endorsed by these companies.
Yes, in India and a number of other markets. In the US, generics are not expected before 2028. We check the patent and registration position for your destination before quoting.
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