Rifaximin bulk supplier for pharma manufacturers

Rifaximin 100 mg/5 mL, 200 mg, 550 mg Suppliers & Bulk Manufacturers

Available Forms: Tablet / Oral Suspension

Available Strengths: 100 mg/5 mL, 200 mg, 550 mg

Reference Brands: Xifaxan (USA), Targaxan (EU), Normix (LATAM)

Rifaximin is a Antibiotics product available as Tablet / Oral Suspension in strengths 100 mg/5 mL, 200 mg, 550 mg. It corresponds to the reference brands Xifaxan (USA), Targaxan (EU), Normix (LATAM). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Rifaximin is a semi-synthetic rifamycin that inhibits bacterial DNA-dependent RNA polymerase. What distinguishes it from the rest of the class is pharmacokinetic rather than microbiological: oral absorption is under one per cent, so it acts almost entirely within the gut lumen and produces essentially no systemic exposure. That is the basis of both its safety profile and its indications.

Use is strength-dependent. The 200 mg strength treats travellers' diarrhoea caused by non-invasive Escherichia coli. The 550 mg strength is used to reduce recurrence of overt hepatic encephalopathy, where it lowers ammonia-producing gut flora, and for irritable bowel syndrome with diarrhoea. Because systemic absorption is minimal, the usual rifamycin concerns about hepatic enzyme induction and drug interactions largely do not apply.

Sourcing notes. The critical issue here is polymorphism, and it catches buyers out. Rifaximin exists in multiple crystalline forms with different solubility, and because solubility governs how much is absorbed, the polymorph affects both efficacy in the gut and systemic exposure. Polymorph identity has been the subject of extensive patent litigation, so a supplier's form determines freedom to operate as much as it determines performance. Require the polymorphic form to be specified and characterised, with supporting XRPD data, before treating any two offers as comparable.

Rifaximin — third party manufacturing & bulk supply

Rifaximin 100 mg/5 mL, 200 mg, 550 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Rifaximin is supplied as Tablet / Oral Suspension — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Rifaximin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Rifaximin is used to treat certain bacterial infections of the gastrointestinal tract. It is commonly prescribed for traveler’s diarrhea caused by noninvasive strains of Escherichia coli, hepatic encephalopathy to reduce the risk of recurrence, and irritable bowel syndrome with diarrhea (IBS-D). Because it acts mainly in the intestines and is minimally absorbed into the bloodstream, it targets bacteria in the gut.

Rifaximin is a semisynthetic derivative of rifamycin, an antibiotic compound originally derived from Streptomyces bacteria. The active pharmaceutical ingredient is formulated into oral tablets or suspensions designed to act locally in the gastrointestinal tract.

Common trade names of rifaximin include Xifaxan, Targaxan, Normix, Rifagut, and several other regional branded generics marketed in different countries.

Rifaximin products such as Xifaxan are marketed by companies including Salix Pharmaceuticals (a subsidiary of Bausch Health Companies), while Normix is associated with Alfasigma and various generic manufacturers worldwide.

The generic name is rifaximin.

Brand names include Xifaxan, Targaxan, Normix, Rifagut, and other country-specific rifaximin brands.

Rifaximin is manufactured in multiple countries including the United States, Italy, India, and other global pharmaceutical manufacturing hubs where companies produce the medicine under GMP-compliant facilities for international markets.