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Procaine Penicillin bulk supplier for pharma manufacturers

Procaine Penicillin 600,000 IU, 1,200,000 IU Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 600,000 IU, 1,200,000 IU

Reference Brands: Wycillin (USA)

Category: Antibiotics

Procaine benzylpenicillin is a depot penicillin injected into muscle once daily, giving penicillin levels for about 24 hours. It is used for syphilis, some pneumonias and, in WHO guidance, for serious infections in newborns and children where hospital care is limited. It is supplied as 600,000 and 1,200,000 IU vials. PharmaTradz sources it for importers, hospitals and tenders, and shares GMP certificates and CoA before you commit.

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Product Description:

Procaine penicillin is benzylpenicillin combined with procaine to form a poorly soluble salt, injected intramuscularly as a depot from which penicillin is released slowly over roughly twenty-four hours. That sustained release is the entire purpose: it allows once-daily dosing where aqueous benzylpenicillin would require administration every four to six hours.

It is used in syphilis, in streptococcal infection and in community-acquired pneumonia in settings where daily attendance is practical but intravenous access is not, and is supplied as 600,000 and 1,200,000 unit presentations.

Route is critical and errors are serious. Procaine penicillin must be given by deep intramuscular injection only. Inadvertent intravascular injection causes Hoigné syndrome — an acute, frightening reaction of anxiety, hallucinations and a sense of impending death, caused by procaine reaching the circulation — and can cause vascular occlusion and tissue necrosis. Labelling and staff instruction must state the route unambiguously.

Sourcing notes. Strength is expressed in international units rather than milligrams, and specifications occasionally mix the two. Distinguish clearly from benzathine penicillin, which is a longer-acting depot used for rheumatic fever prophylaxis; the two are not interchangeable. Manufacture requires sterile suspension capability. WHO classifies it under Access.

Procaine Penicillin — third party manufacturing & bulk supply

Procaine Penicillin 600,000 IU, 1,200,000 IU is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Procaine Penicillin is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Procaine Penicillin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Deep intramuscular injection only, once daily; accidental intravenous injection can cause serious reactions.

Yes, for neurosyphilis (with probenecid) and congenital syphilis, where benzathine penicillin is not suitable.

As 600,000 IU and 1,200,000 IU powder or ready suspension vials, depending on the market.

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