Isoniazid + Rifampicin 300mg+150mg, 100mg+150mg Suppliers & Bulk Manufacturers
Available Forms: Capsules / Tablet
Available Strengths: 300mg+150mg, 100mg+150mg
Reference Brands: Rifamate (USA), IsonaRif (USA), Rifinah(UK)
Category: Antibiotics
Isoniazid + Rifampicin is a fixed-dose antitubercular antibiotic combination used for the treatment and prevention of tuberculosis (TB). It works by inhibiting bacterial cell wall synthesis (isoniazid) and blocking RNA transcription (rifampicin), providing a synergistic effect and reducing the risk of drug resistance.
Product Description:
Isoniazid + Rifampicin, also referred to as Isoniazid + Rifampin, is a fixed-dose combination medication used for the treatment of tuberculosis (TB). This combination contains two potent first-line antitubercular agents: Isoniazid, which inhibits mycolic acid synthesis in the mycobacterial cell wall, and Rifampicin, which blocks bacterial RNA transcription. Together, they provide synergistic bactericidal activity, making the combination highly effective against Mycobacterium tuberculosis.
The medication is designed for oral administration and is commonly used alongside other antituberculosis drugs as part of a multidrug regimen to enhance efficacy and prevent drug resistance. Available in both tablet and syrup formulations, Isoniazid + Rifampicin allows for flexible dosing in adults and pediatric patients. Its fixed-dose combination simplifies therapy, ensures adherence, and supports consistent therapeutic outcomes. With a well-established safety profile and proven effectiveness, Isoniazid + Rifampicin remains a cornerstone in global TB management strategies.
Isoniazid + Rifampicin — third party manufacturing & bulk supply
Isoniazid + Rifampicin 300mg+150mg, 100mg+150mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Isoniazid + Rifampicin is supplied as Capsules / Tablet — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Isoniazid + Rifampicin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Isoniazid + Rifampicin →Frequently Asked Questions
Isoniazid + Rifampicin combination is used for the treatment of active Mycobacterium tuberculosis (TB) infection. It is a first-line therapy for tuberculosis and is also used in certain latent TB cases as part of combination therapy. The combination provides synergistic bactericidal activity against TB bacteria and helps prevent drug resistance.
The combination contains two active ingredients: isonicotinic acid hydrazide (Isoniazid) and rifampicin (Rifampin). Both act together to inhibit mycobacterial cell wall synthesis and RNA transcription, resulting in effective killing of Mycobacterium tuberculosis. Excipients in tablets or syrups are included to allow stability, accurate dosing, and oral administration.
Common trade names include Rifamate, Isonorif, and Rifinah, though specific brands vary by region and manufacturer.
Manufacturers include Sanofi, Cipla, Macleods, Lupin, and other regional pharmaceutical companies producing fixed-dose combinations for TB treatment.
Isoniazid (isonicotinic acid hydrazide) + Rifampicin (rifampin).
Rifamate, Isonorif, Rifinah, and other regional brand names depending on country regulations.
Global manufacturing includes India, Europe, and the USA. Major manufacturers are Sanofi (Europe), Cipla and Macleods (India), and Lupin (India).
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