Daptomycin bulk supplier for pharma manufacturers

Daptomycin 350 mg, 500 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 350 mg, 500 mg

Reference Brands: Cubicin (USA/EU)

Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of serious Gram-positive bacterial infections, including complicated skin and soft tissue infections, bloodstream infections (bacteremia), and right-sided infective endocarditis caused by Staphylococcus aureus. It works by disrupting bacterial cell membrane function, leading to rapid bacterial cell death.

Get Enquiry / Request Bulk Quote

Usually answered within 48 hours | GMP documents shared before you commit

Manufacture or export Daptomycin? List it or send an offer →

Product Description:

Daptomycin is a cyclic lipopeptide with a mechanism unlike other Gram-positive agents: it inserts into the bacterial cell membrane in a calcium-dependent manner, causing rapid depolarisation and cell death without lysis. It is bactericidal against methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci and other resistant Gram-positive organisms.

It is indicated for complicated skin and skin structure infection and for S. aureus bacteraemia including right-sided endocarditis, and is supplied as lyophilised powder at 350 and 500 mg.

One absolute limitation must be understood before it is supplied for respiratory use. Daptomycin is inactivated by pulmonary surfactant and is therefore ineffective in pneumonia. This is not a matter of reduced efficacy but of the drug not working at that site at all, and a specification listing daptomycin for a respiratory indication has been written in error.

Creatine kinase monitoring is required, since myopathy and rarely rhabdomyolysis occur.

Sourcing notes. Daptomycin is off patent and generic supply is well established from several manufacturers, so this is genuinely sourceable. Manufacture requires lyophilisation capability at the specific plant. WHO classifies daptomycin under Reserve, which restricts its use to confirmed resistant infection under stewardship control and affects tender eligibility.

Daptomycin — third party manufacturing & bulk supply

Daptomycin 350 mg, 500 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Daptomycin is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Daptomycin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

Request a quote for Daptomycin →

Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.

Back to Listing

Frequently Asked Questions

Daptomycin is listed as Injection in 350 mg, 500 mg. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Daptomycin is referenced against Cubicin (USA/EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.