Prednisolone Acetate Eye Drops 1% w/v Suppliers & Bulk Manufacturers

Available Forms: Eye Drops

Available Strengths: 1% w/v

Reference Brands: Pred Forte(USA/EU/UK), Pred Mild, OmniPred, Econopred

Category: Opthalmology

Prednisolone Acetate (1% w/v) is a potent corticosteroid ophthalmic suspension used to reduce inflammation in the conjunctiva, cornea, and anterior segment of the eye. It effectively manages conditions like allergic conjunctivitis, post-operative inflammation, and chemical or radiation-induced ocular inflammation. Being a suspension, it must be thoroughly shaken before application to ensure uniform dosing

Product Description:

Prednisolone acetate 1% is the standard potent topical corticosteroid for the eye and the comparator against which others are measured. The acetate ester is lipophilic, so it penetrates the intact cornea well and reaches useful concentrations in the anterior chamber, where it suppresses the inflammatory cascade — cell migration, capillary leak, fibrin deposition and later scarring.

It is used for anterior uveitis, after ocular surgery, for chemical and thermal injury, and in other inflammatory conditions of the anterior segment, dosed frequently at first and tapered. It is a suspension, and this matters: the drug settles, so a bottle that is not shaken thoroughly delivers a dose that may be a fraction of, or several times, what is intended. The risks of prolonged use are well defined — raised intraocular pressure in steroid responders, posterior subcapsular cataract, delayed epithelial healing, and worsening of herpes simplex keratitis and fungal infection, which is why steroids are never started in a red eye without a diagnosis.

Sourcing notes. Resuspendability is the central quality attribute; caking on storage is the common failure and makes the product effectively unusable. Off patent, inexpensive, and on essential medicines lists. Preservative-free and unit-dose presentations exist for frequent dosing regimens.