mavacamten bulk supplier for pharma manufacturers

Mavacamten 2.5mg, 5mg, 10mg, 15mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 2.5mg, 5mg, 10mg, 15mg

Reference Brands: Camzyos (USA/EU)

Mavacamten is a first-in-class cardiac myosin inhibitor designed for the treatment of obstructive hypertrophic cardiomyopathy (oHCM) in adults. It targets the underlying mechanism of disease by reducing excessive cardiac contractility, improving heart function, and alleviating symptoms such as shortness of breath, fatigue, and exercise intolerance.

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Product Description:

Mavacamten is a cardiac myosin inhibitor and the first drug to target the underlying biology of hypertrophic cardiomyopathy rather than its symptoms. In that condition, mutations make the heart's contractile machinery form too many force-generating bridges, so the muscle contracts too hard and relaxes poorly, and the thickened septum obstructs outflow. Mavacamten reduces the number of bridges, easing contraction and improving filling.

It is used for symptomatic obstructive hypertrophic cardiomyopathy in adults, and in trials it improved exercise capacity, symptoms and outflow obstruction, and reduced the need for septal reduction procedures. Because the intended effect is reduced contraction, excessive dosing can cause systolic dysfunction and heart failure, so treatment is guided by echocardiography and by plasma levels, with dosing individualised. The US label was eased in 2025, reducing the frequency of echocardiographic monitoring and narrowing contraindications, but risk management remains part of prescribing. It is metabolised by CYP2C19, so genotype and interacting drugs affect exposure, and it is contraindicated in pregnancy.

Sourcing notes. Originator product, on patent, no generic. Distribution is controlled and prescribing requires enrolment in a risk programme in several markets. Supply is through authorised distribution.

Mavacamten — third party manufacturing & bulk supply

Mavacamten 2.5mg, 5mg, 10mg, 15mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Mavacamten is supplied as Capsules — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Mavacamten listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

mavacamten is listed as Capsules in 2.5mg, 5mg, 10mg, 15mg. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

mavacamten is referenced against Camzyos (USA/EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.