Amlodipine/Benazepril bulk supplier for pharma manufacturers

Amlodipine/Benazepril Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 2.5 mg/10 mg, 5 mg/10 mg, 5 mg/20 mg

Reference Brands: Lotrel(USA/EU)

Amlodipine/Benazepril is a combination medication used to treat high blood pressure (hypertension). It contains amlodipine, a calcium channel blocker that relaxes and widens blood vessels, and benazepril, an ACE inhibitor that reduces constriction of blood vessels. Together, they help lower blood pressure, improve blood flow, and reduce the risk of heart attack, stroke, and kidney problems.

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Product Description:

This capsule combines amlodipine, a long-acting dihydropyridine calcium channel blocker, with benazepril, an ACE inhibitor. Amlodipine relaxes arterial smooth muscle by blocking calcium entry; benazepril reduces angiotensin II formation, lowering vasoconstriction and aldosterone. Combining a calcium channel blocker with a renin-angiotensin blocker is one of the preferred two-drug combinations in hypertension guidelines, because the mechanisms are complementary and one offsets the other's main adverse effect: ACE inhibition reduces the ankle swelling amlodipine causes.

It is used when a single agent does not control blood pressure. The ACCOMPLISH trial found this pairing reduced cardiovascular events more than an ACE inhibitor with a thiazide diuretic, which shaped guideline preference. Adverse effects include cough from the ACE inhibitor, ankle oedema, dizziness and, rarely, angioedema. It is contraindicated in pregnancy, and potassium and renal function are checked after starting. Dose adjustment is needed in renal impairment.

Sourcing notes. Off patent, with generic capsules widely available in the US and elsewhere. The fixed-dose combination is registered as a single product, so it needs its own bioequivalence data rather than relying on the two single agents. Several strength combinations exist and are not interchangeable.

Amlodipine/Benazepril — third party manufacturing & bulk supply

Amlodipine/Benazepril is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Amlodipine/Benazepril is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Amlodipine/Benazepril listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Amlodipine/Benazepril is listed as Tablets in 2.5 mg/10 mg, 5 mg/10 mg, 5 mg/20 mg. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Amlodipine/Benazepril is referenced against Lotrel(USA/EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.