Quinidine Gluconate 200 mg, 324 mg, 300 mg/5 mL Suppliers & Bulk Manufacturers

Available Forms: Tablet / Oral Solution

Available Strengths: 200 mg, 324 mg, 300 mg/5 mL

Reference Brands: Generic formulations marketed under different names

Category: Heart Disorder

Quinidine Gluconate is a Heart Disorder product available as Tablet / Oral Solution in strengths 200 mg, 324 mg, 300 mg/5 mL. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Quinidine is a naturally derived alkaloid and the D-isomer of quinine, originally isolated from the bark of the Cinchona tree and related plant species. First described in 1848, it holds historical significance as the first antiarrhythmic medication, classified as a class Ia agent. Quinidine exerts its therapeutic effects by blocking sodium and potassium currents in cardiac cells, thereby prolonging the action potential and helping to stabilize abnormal heart rhythms. It has been moderately effective in the acute conversion of atrial fibrillation to normal sinus rhythm.

Despite its efficacy, quinidine use declined over the decades due to notable side effects, including a risk of syncope and life-threatening ventricular arrhythmias, a phenomenon historically referred to as “quinidine syncope.” Nevertheless, quinidine retains an important role in the management of specific cardiac conditions where other therapies may be less effective. It is used in the treatment of Brugada syndrome, short QT syndrome, and idiopathic ventricular fibrillation, offering targeted rhythm control for patients with these rare and potentially life-threatening arrhythmias. Quinidine continues to be recognized for its unique mechanism of action and historical significance in the evolution of cardiac arrhythmia management.