Tirofiban Hydrochloride 2.5 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 2.5 mg/mL

Reference Brands: Aggrastat (USA)

Category: Heart Disorder

Tirofiban Hydrochloride is a Heart Disorder product available as Injection in strengths 2.5 mg/mL. It corresponds to the reference brand Aggrastat (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Tirofiban, marketed under the brand name Aggrastat, is a potent antiplatelet medication belonging to the class of glycoprotein IIb/IIIa inhibitors. It acts as a small-molecule inhibitor that blocks the interaction between fibrinogen and the platelet integrin receptor GP IIb/IIIa, preventing platelet aggregation and thrombus formation. Tirofiban was developed through pharmacophore-based virtual screening, making it the first drug of its kind identified using this approach.

Clinically, tirofiban is indicated to reduce the risk of thrombotic cardiovascular events, including death, myocardial infarction, or refractory ischemia requiring repeat cardiac procedures, in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). Its rapid onset of action and reversible platelet inhibition make it a valuable therapy in acute cardiac care, particularly during hospital-managed interventions such as percutaneous coronary procedures.

Tirofiban is administered intravenously under strict medical supervision in hospital settings due to its potent antiplatelet effects. Continuous monitoring is required to manage the risk of bleeding and ensure optimal therapeutic outcomes. This targeted mechanism of action allows tirofiban to provide effective cardiovascular protection while minimizing systemic complications.