Fenofibrate Caplets and Capsules Suppliers & Bulk Manufacturers

Available Forms: Caplets and Capsules

Available Strengths: 67 mg, 135 mg, 160 mg, and 145 mg

Reference Brands: Tricor (US)

Category: Heart Disorder

Fenofibrate caplets and capsules in micronised, nanoparticle and fenofibric acid forms, 67 mg to 160 mg, a fibrate for raised triglycerides, for importers, distributors, hospitals and tender buyers.

Product Description:

Fenofibrate is a fibrate that activates the nuclear receptor PPAR-alpha. This increases fatty acid breakdown, speeds clearance of triglyceride-rich particles and raises HDL cholesterol. It is a prodrug converted to fenofibric acid, and it dissolves poorly, so makers use different technologies to improve absorption. That explains the varied strengths: 67 mg micronised capsules, 160 mg tablets, 145 mg nanoparticle tablets and 135 mg delayed-release capsules of choline fenofibrate. They are not interchangeable milligram for milligram.

Fenofibrate is used with diet for severe hypertriglyceridaemia and mixed dyslipidaemia, especially when a statin is unsuitable or not enough alone. Some forms are taken with food and others without regard to meals, so the exact product label applies. Pharmacists check kidney function, as doses are cut or the drug avoided in significant renal impairment, and liver tests are monitored. Muscle pain needs prompt review, especially with a statin. It strengthens warfarin and is avoided in gallbladder disease.

Sourcing notes. Name the technology as well as the strength: micronised capsule, tablet, nanoparticle tablet or choline fenofibrate capsule. A generic must match the reference product of the same technology, so ask for the bioequivalence report with a CTD or ACTD dossier. Request a CoA per batch, a GMP certificate and a CoPP where needed. Blisters or bottles are stored at room temperature, protected from moisture, without cold chain, and stability data should match your climatic zone, including Zone IVb. It is prescription-only.