Inamrinone Lactate 10 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 10 mg/mL

Reference Brands: Generic formulations marketed under different names

Category: Heart Disorder

Inamrinone Lactate is a Heart Disorder product available as Injection in strengths 10 mg/mL. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Inamrinone, also known as amrinone and marketed under the brand name Inocor, is a phosphodiesterase-3 (PDE3) inhibitor used in the management of congestive heart failure. It exerts a positive inotropic effect, enhancing the contractility of cardiac muscle and improving cardiac output in patients with heart failure. The drug achieves this by selectively increasing high-gain calcium-induced calcium release (CICR) within cardiac myocytes, which promotes stronger heart contractions. This effect is mediated through phosphorylation pathways involving cAMP-dependent protein kinase A (PKA) and Ca²⁺/calmodulin-dependent kinase, resulting in improved cardiac function.

Inamrinone is administered intravenously under strict medical supervision, typically in hospital or critical care settings, and is used for short-term management of severe or acute heart failure in patients who do not adequately respond to conventional therapies. By enhancing myocardial contractility and reducing vascular resistance, inamrinone provides symptomatic relief and can improve hemodynamic parameters in critically ill patients, making it an important therapeutic option in advanced heart failure management.