Tafamidis Capsules 20 mg, 61 mg Suppliers & Bulk Manufacturers

Available Forms: Soft capsules

Available Strengths: 20 mg, 61 mg

Pack Sizes: 30 capsules

Reference Brands: Vyndaqel, Vyndamax

Category: Heart Disorder

Tafamidis is a transthyretin stabiliser used for transthyretin amyloidosis of the heart and nerves. PharmaTradz handles enquiries for tafamidis supply and for API and dossier partners.

Product Description:

Tafamidis treats transthyretin amyloidosis (ATTR). Transthyretin is a blood protein that normally travels as a group of four. In ATTR the group falls apart, and the single pieces fold wrongly and build up as amyloid in the heart and nerves. Tafamidis binds to the protein and holds the four pieces together, which slows the disease.

The 61 mg capsule (tafamidis free acid) and 80 mg as four 20 mg capsules (tafamidis meglumine) are used for ATTR cardiomyopathy, where they reduce deaths and heart-related hospital stays. In the EU the 20 mg capsule is also used for early nerve disease (polyneuropathy). It is taken once a day for life, which makes it one of the costliest heart medicines and a frequent named-patient and access request.

Sourcing notes. Tafamidis API is produced by several manufacturers, but patent protection on the finished product differs by country, and in the US generic entry has been delayed by patent settlements. We confirm what can lawfully be supplied for each destination before quoting, and handle innovator supply through authorised routes where needed. Room-temperature storage.