Selexipag bulk supplier for pharma manufacturers

Selexipag Suppliers & Bulk Manufacturers

Available Forms: Tablets / Injection

Available Strengths: 200 mcg, 400 mcg, 600 mcg, 800 mcg, 1000 mcg, 1200 mcg, 1400 mcg, 1600 mcg

Reference Brands: Uptravi (USA/EU)

Selexipag is a Heart Disorder product available as Tablets / Injection in strengths 200 mcg, 400 mcg, 600 mcg, 800 mcg, 1000 mcg, 1200 mcg, 1400 mcg, 1600 mcg. It corresponds to the reference brand Uptravi (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Selexipag is a selective prostacyclin (IP) receptor agonist indicated for the long-term treatment of pulmonary arterial hypertension (PAH). It is used to delay disease progression and reduce the risk of hospitalization associated with PAH. Developed by Actelion, Selexipag represents an advanced, non-prostanoid therapeutic option that targets the prostacyclin pathway, a key mechanism involved in pulmonary vascular remodeling and increased pulmonary arterial pressure.

After oral or intravenous administration, Selexipag is rapidly metabolized into its active metabolite, ACT-333679 (also known as MRE-269), which exhibits a high affinity for the prostacyclin receptor. Activation of this receptor leads to vasodilation of the pulmonary arteries, inhibition of smooth muscle cell proliferation, and improved pulmonary blood flow. Unlike traditional prostacyclin analogues, Selexipag offers targeted receptor activity with a more convenient dosing profile.

Selexipag can be administered as oral tablets for chronic therapy or intravenously for patients who are temporarily unable to take oral medication. It is commonly used as monotherapy or in combination with other PAH treatments, including endothelin receptor antagonists and phosphodiesterase-5 inhibitors, making it a valuable option in comprehensive PAH management strategies.

Selexipag — third party manufacturing & bulk supply

Selexipag is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Selexipag is supplied as Tablets / Injection — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Selexipag listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Selexipag is used for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce the risk of hospitalization related to PAH.

Selexipag is a chemically synthesized small-molecule drug that acts as a selective agonist of the prostacyclin (IP) receptor.

The trade name of Selexipag is Uptravi.

Selexipag (Uptravi) is manufactured and marketed by Actelion Pharmaceuticals Ltd., a Janssen Pharmaceutical company.

The generic name of Uptravi is Selexipag.

The brand name of Selexipag is Uptravi.

Selexipag is manufactured at Actelion/Janssen approved pharmaceutical manufacturing facilities, primarily located in Europe and the United States, in compliance with international regulatory standards.