Lactitol Monohydrate Powder 10 g sachets; bulk powder Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: 10 g sachets; bulk powder

Reference Brands: Pizensy (US), Importal (EU)

Category: Gastrointestinal Drugs

Lactitol powder is an osmotic laxative made from lactose, used for chronic constipation and to reduce ammonia in hepatic encephalopathy. It reaches the colon undigested, where it draws in water and softens stools. It is usually supplied in 10 g sachets; brands include Importal and Pizensy. We quote from GMP-approved manufacturers and confirm document status, lead time and MOQ for each order.

Product Description:

Lactitol is a sugar alcohol made from lactose. It is not absorbed or broken down in the small intestine, so it reaches the colon intact, where bacteria ferment it into short-chain fatty acids. These acidify the colon and draw water into the bowel by osmosis, softening stool and increasing its volume. It works in a similar way to lactulose but is supplied as a powder, which some patients find easier to take than lactulose syrup.

It is used for chronic constipation in adults, with an effect usually seen within a day or two, and it was approved in the US in 2020 for chronic idiopathic constipation. Acidification of the colon also reduces ammonia absorption, so higher doses are used in hepatic encephalopathy in some countries. Bloating, flatulence and abdominal discomfort are common at first. It is not suitable for people with galactosaemia or intestinal obstruction, and electrolytes should be monitored in older or frail patients on long-term treatment.

Sourcing notes. Lactitol is registered as a medicine for constipation in Europe and the US, and it is also a food ingredient, so the grade and intended use must be clear. Pharmaceutical grade should meet the pharmacopoeial monograph. The powder is hygroscopic and must be protected from moisture.