Magnesium Trisilicate and Pyridoxine HCl Tablets Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: -

Reference Brands:

Category: Gastrointestinal Drugs

Magnesium trisilicate relieves the pain and discomfort of indigestion and heartburn.

Product Description:

This tablet pairs magnesium trisilicate, a slow-acting antacid, with pyridoxine (vitamin B6). Magnesium trisilicate neutralises gastric acid gradually and forms a gelatinous silica layer that may coat the mucosa. Pyridoxine is included for its long use against nausea, particularly nausea of early pregnancy, where it is an established first-line treatment on its own or combined with doxylamine.

The combination is aimed at indigestion accompanied by nausea. Evidence supporting this particular pairing is limited, and each component can be given separately at a dose chosen for the patient. Magnesium tends to loosen stool, and it accumulates in renal impairment. Long-term magnesium trisilicate use has been associated with silica kidney stones. Pyridoxine is safe at usual doses, but prolonged high intake causes sensory neuropathy. Antacids reduce absorption of tetracyclines, fluoroquinolones, iron and levothyroxine.

Sourcing notes. A fixed-dose combination registered mainly in South Asian markets. Regulators in several countries have reviewed antacid combinations for rationality, and this one is unlikely to be registrable in regulated markets, so confirm the destination regulator accepts it first. Buyers should specify the strength of each component when enquiring.