Etelcalcetide 2.5 mg/mL, 5 mg/mL, 10 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 2.5 mg/mL, 5 mg/mL, 10 mg/mL

Reference Brands: Parsabiv (USA/EU)

Category: Critical Care

Etelcalcetide is a Critical Care product available as Injection in strengths 2.5 mg/mL, 5 mg/mL, 10 mg/mL. It corresponds to the reference brand Parsabiv (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Etelcalcetide is a synthetic peptide calcimimetic and calcium-sensing receptor (CaSR) agonist used for the treatment of secondary hyperparathyroidism (sHPT) in adults with chronic kidney disease (CKD) on hemodialysis. Composed of seven D-amino acids, etelcalcetide is administered intravenously and functions by mimicking calcium to allosterically activate the CaSR expressed on parathyroid cells. Activation of this receptor suppresses the synthesis and secretion of parathyroid hormone (PTH), helping to reduce elevated PTH levels commonly observed in patients with CKD.

By lowering PTH, etelcalcetide also contributes to the regulation of serum calcium and phosphorus levels, addressing the imbalances in calcium-phosphate homeostasis that can occur in chronic kidney disease. Its targeted mechanism provides effective management of sHPT, which is associated with bone and cardiovascular complications in CKD patients.

Etelcalcetide is marketed under the brand name Parsabiv and is delivered via pre-filled intravenous vials for use during hemodialysis sessions. It represents an important therapeutic option for controlling PTH and mineral metabolism, improving patient outcomes, and reducing the risks associated with chronic elevations of parathyroid hormone in the CKD population.