Argatroban 100 mg/ mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 100 mg/ mL

Reference Brands: Generic formulations marketed under different names

Category: Critical Care

Argatroban is a Critical Care product available as Injection in strengths 100 mg/ mL. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Argatroban is an intravenous anticoagulant medication used for the prevention and treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT), a rare but potentially life-threatening immune-mediated complication associated with heparin therapy. It belongs to the class of direct thrombin inhibitors and provides effective anticoagulation without cross-reactivity with heparin antibodies.

Argatroban works by directly and reversibly inhibiting thrombin, thereby preventing fibrin formation, platelet aggregation, and clot development. It is commonly used in hospitalized and critical care settings, including during percutaneous coronary interventions in patients with HIT who require ongoing anticoagulation. Due to its rapid onset of action and short half-life, argatroban allows precise dose adjustments and close control of anticoagulant effects.

The drug is administered by continuous intravenous infusion and requires careful monitoring using activated partial thromboplastin time (aPTT). Argatroban is primarily metabolized in the liver, making it suitable for patients with renal impairment, though dose adjustments are necessary in hepatic dysfunction. Awareness of potential drug interactions, bleeding risks, and patient-specific factors is essential for safe and effective therapy. When used appropriately, argatroban remains a valuable and reliable anticoagulant option in the management of HIT.