Conivaptan Hydrochloride 20 mg/100 mL Suppliers & Bulk Manufacturers

Available Forms: Infusion

Available Strengths: 20 mg/100 mL

Reference Brands: Vaprisol (USA)

Category: Critical Care

Conivaptan Hydrochloride is a Critical Care product available as Infusion in strengths 20 mg/100 mL. It corresponds to the reference brand Vaprisol (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Conivaptan hydrochloride is a vasopressin receptor antagonist used for the treatment of hyponatremia, a condition characterized by abnormally low sodium levels in the blood. It is commonly prescribed for hospitalized patients with euvolemic or hypervolemic hyponatremia, including cases associated with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), heart failure, or other medical conditions that affect fluid balance. Conivaptan is marketed under the brand name Vaprisol and is administered intravenously in a controlled hospital setting.

Conivaptan works by blocking the action of vasopressin, also known as antidiuretic hormone (ADH), at V1A and V2 receptors. By inhibiting these receptors, the drug promotes the excretion of free water without significant loss of electrolytes, helping to gradually increase serum sodium levels and restore fluid balance in the body. This mechanism makes it particularly useful in managing conditions where excess water retention leads to dilutional hyponatremia.

Approved in 2004, conivaptan has become an important treatment option in critical care and hospital medicine. Its targeted action and controlled administration allow healthcare professionals to effectively manage sodium imbalances while closely monitoring patient response and safety.