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Conivaptan Hydrochloride bulk supplier for pharma manufacturers

Conivaptan Hydrochloride Suppliers & Bulk Manufacturers

Available Forms: Infusion

Available Strengths: 20 mg/100 mL

Reference Brands: Vaprisol (USA)

Category: Critical Care

Conivaptan Hydrochloride is available in Infusion and strengths such as 20 mg/100 mL. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Conivaptan Hydrochloride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Conivaptan Hydrochloride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Conivaptan hydrochloride is a vasopressin receptor antagonist used for the treatment of hyponatremia, a condition characterized by abnormally low sodium levels in the blood. It is commonly prescribed for hospitalized patients with euvolemic or hypervolemic hyponatremia, including cases associated with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), heart failure, or other medical conditions that affect fluid balance. Conivaptan is marketed under the brand name Vaprisol and is administered intravenously in a controlled hospital setting.

Conivaptan works by blocking the action of vasopressin, also known as antidiuretic hormone (ADH), at V1A and V2 receptors. By inhibiting these receptors, the drug promotes the excretion of free water without significant loss of electrolytes, helping to gradually increase serum sodium levels and restore fluid balance in the body. This mechanism makes it particularly useful in managing conditions where excess water retention leads to dilutional hyponatremia.

Approved in 2004, conivaptan has become an important treatment option in critical care and hospital medicine. Its targeted action and controlled administration allow healthcare professionals to effectively manage sodium imbalances while closely monitoring patient response and safety.

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Frequently Asked Questions

Conivaptan hydrochloride is used to treat euvolemic and hypervolemic hyponatremia in hospitalized patients. It helps correct low sodium levels that may occur in conditions such as heart failure, syndrome of inappropriate antidiuretic hormone secretion (SIADH), and other medical disorders.

Conivaptan hydrochloride is a synthetic non-peptide vasopressin receptor antagonist designed to block both V1A and V2 vasopressin receptors. By blocking these receptors, it promotes the excretion of free water without significant loss of electrolytes.

The main trade name of conivaptan hydrochloride is Vaprisol.

Vaprisol (conivaptan hydrochloride) was developed and marketed by Astellas Pharma for hospital use in the treatment of hyponatremia.

The generic name of Vaprisol is conivaptan hydrochloride.

A well-known brand name of conivaptan hydrochloride is Vaprisol.

Conivaptan hydrochloride injection is manufactured in GMP-certified pharmaceutical facilities that produce sterile injectable medicines for hospital and critical care use, following international regulatory standards.

Yes, Conivaptan Hydrochloride is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Conivaptan Hydrochloride is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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