Entrectinib 100 mg, 200 mg Suppliers & Bulk Manufacturers
Available Forms: Capsules
Available Strengths: 100 mg, 200 mg
Reference Brands: Rozlytrek (USA/EU)
Category: Oncology Cancer Care
Entrectinib is a Oncology Cancer Care product available as Capsules in strengths 100 mg, 200 mg. It corresponds to the reference brand Rozlytrek (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
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Product Description:
Entrectinib is an oral, small-molecule tyrosine kinase inhibitor used in the treatment of specific advanced cancers driven by genetic alterations. It is approved for use in adults with metastatic non-small cell lung cancer (NSCLC) that is ROS1-positive, as well as in adults and pediatric patients aged one month and older with solid tumors that harbor an NTRK gene fusion. These cancers are typically aggressive and may have limited treatment options, making targeted therapies like entrectinib especially valuable.
Entrectinib works by selectively inhibiting the activity of TRK, ROS1, and ALK proteins, which play a critical role in cancer cell signaling, growth, and survival. By blocking these abnormal signaling pathways, entrectinib helps slow or stop tumor growth and may lead to the death of cancer cells. One of its notable features is its ability to penetrate the central nervous system, making it effective in treating cancers that have spread to the brain.
Entrectinib — third party manufacturing & bulk supply
Entrectinib 100 mg, 200 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Entrectinib is supplied as Capsules — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Entrectinib listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
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Frequently Asked Questions
Entrectinib is used for the treatment of NTRK fusion-positive solid tumors and ROS1-positive non-small cell lung cancer in patients whose disease is metastatic or where surgical resection is likely to result in severe morbidity.
Entrectinib is a small-molecule synthetic tyrosine kinase inhibitor developed to selectively inhibit TRK, ROS1, and ALK proteins involved in cancer cell growth.
The trade name of entrectinib is Rozlytrek.
Entrectinib (Rozlytrek) is developed and marketed by Roche, through its subsidiary Genentech.
The generic name is entrectinib.
The brand name is Rozlytrek.
Entrectinib is manufactured by Roche/Genentech at approved pharmaceutical manufacturing facilities that supply the USA, EU, and UK markets.
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