Imetelstat 47 mg, 188 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 47 mg, 188 mg

Reference Brands: Generic formulations marketed under different names

Category: Oncology Cancer Care

Imetelstat is a Oncology Cancer Care product available as Injection in strengths 47 mg, 188 mg. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Imetelstat sodium is a targeted anti-cancer therapy used in the treatment of myelodysplastic syndromes (MDS) associated with transfusion-dependent anemia. It is marketed under the brand name Rytelo and represents a first-in-class telomerase inhibitor designed to address the underlying disease biology rather than only managing symptoms. Imetelstat is an oligonucleotide-based medication developed to selectively inhibit telomerase, an enzyme that is highly active in rapidly dividing cells, including malignant cancer cells.

Telomerase plays a crucial role in maintaining telomere length, allowing cancer cells to continue dividing uncontrollably. By blocking telomerase activity, imetelstat causes progressive telomere shortening, which limits the ability of malignant stem and progenitor cells to proliferate. This process ultimately leads to cancer cell death and a reduction in abnormal cell clones responsible for disease progression. Through this mechanism, imetelstat helps improve bone marrow function and reduces transfusion dependence in eligible patients.