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Silver Diamine Fluoride bulk supplier for pharma manufacturers

Silver Diamine Fluoride Suppliers & Bulk Manufacturers

Available Forms: Topical Solution

Available Strengths: 38%

Reference Brands: Advantage Arrest (USA), Saforide (Japan/ India)

Category: Dental / Oral Health

Silver Diamine Fluoride is available in Topical Solution and strengths such as 38%. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Silver Diamine Fluoride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Silver Diamine Fluoride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Silver diamine fluoride (SDF) is a topical dental solution widely used for the management and arrest of dental caries. In recent years, it has gained significant popularity among clinicians and patients because of its ability to stop the progression of cavities quickly and effectively after application. SDF is especially useful in preventive and minimally invasive dentistry, making it an important option for treating young children, elderly patients, and individuals with special healthcare needs who may not tolerate complex dental procedures.

The effectiveness of silver diamine fluoride is attributed to the combined actions of silver and fluoride. Silver provides strong antibacterial properties that help reduce the number of cariogenic bacteria responsible for tooth decay, while fluoride supports the remineralization of tooth structure and strengthens enamel and dentin. Studies have shown that SDF can inhibit the growth of harmful oral bacteria and disrupt biofilm formation, which plays a key role in the development of dental caries. In addition, SDF has demonstrated activity against certain fungal organisms such as Candida species.

Another important benefit of SDF treatment is its ability to increase the surface microhardness of carious lesions. By enhancing mineral deposition and supporting calcium uptake in tooth tissues, it helps reduce dentin demineralization and stabilizes affected areas of the tooth. Due to these properties, silver diamine fluoride is increasingly recognized as an effective and practical solution for modern caries management programs.

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Frequently Asked Questions

Silver diamine fluoride is used to arrest and prevent dental caries and to reduce tooth sensitivity. It is applied topically by dental professionals to stop the progression of cavities, particularly in children, elderly patients, and individuals who may not tolerate more invasive dental treatments.

Silver diamine fluoride is made from a combination of silver, fluoride, ammonia, and water, forming a stable alkaline solution. Silver acts as an antimicrobial agent, while fluoride helps strengthen tooth structure and promote remineralization.

Common trade names of silver diamine fluoride include Advantage Arrest, Saforide, e-SDF, and Riva Star.

One widely used brand, Advantage Arrest, is manufactured by Elevate Oral Care, while other brands are produced by dental product manufacturers in Japan, Europe, and other international markets.

The generic name is silver diamine fluoride.

Some well-known brand names include Advantage Arrest, Saforide, e-SDF, and Riva Star.

Silver diamine fluoride products are manufactured in regulated dental and pharmaceutical manufacturing facilities in countries such as the United States, Japan, and other regions supplying global dental markets.

Yes, Silver Diamine Fluoride is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Silver Diamine Fluoride is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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