Naloxegol Oxalate 12.5 mg, 25 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 12.5 mg, 25 mg
Reference Brands: Movantik (USA), Moventig (EU)
Category: Gastrointestinal Drugs
Naloxegol oxalate is a peripherally acting μ‑opioid receptor antagonist used to treat opioid‑induced constipation in adults with chronic non‑cancer pain who have not responded adequately to laxatives. It is a PEGylated derivative of naloxone designed to act mainly in the gastrointestinal tract without affecting central pain relief. Naloxegol is taken orally once daily, usually on an empty stomach. Available in 12.5 mg and 25 mg tablets, it helps improve bowel movement frequency. Common side effects include abdominal pain, diarrhea, nausea, flatulence, and headache.
Product Description:
Naloxegol oxalate is an orally active gastrointestinal drug belonging to the class of peripherally acting μ‑opioid receptor antagonists (PAMORAs), specifically designed to treat opioid‑induced constipation (OIC) in adult patients with chronic non‑cancer pain who have had an inadequate response to traditional laxatives. Because it is a PEGylated derivative of naloxone, naloxegol has significantly reduced ability to cross the blood‑brain barrier, so it preferentially blocks opioid receptors in the gastrointestinal tract without interfering with the central analgesic effects of opioids. This selectivity helps restore normal bowel function by counteracting the opioid‑induced slowing of gastrointestinal motility while maintaining pain control. Naloxegol is available in tablets of 12.5 mg and 25 mg, taken once daily on an empty stomach. In the United States, it is marketed under the brand Movantik, and in the European Union and United Kingdom, it is marketed as Moventig. The dosing may be adjusted for patients with renal impairment, and treatment should be discontinued if opioid therapy is stopped. Common side effects include abdominal pain, diarrhea, nausea, flatulence, vomiting, and headache, generally mild to moderate in severity.
Naloxegol Oxalate — third party manufacturing & bulk supply
Naloxegol Oxalate 12.5 mg, 25 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Naloxegol Oxalate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Naloxegol Oxalate →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Naloxegol oxalate is used to treat
Naloxegol is a PEGylated derivative of naloxone, formulated as
The main trade names for naloxegol are
Naloxegol products such as Movantik and Moventig are manufactured and marketed by companies licensed in respective regions for opioid‑induced constipation treatment.
The generic name of Movantik is
Brand names for naloxegol include
Naloxegol oxalate tablets are manufactured under regulated pharmaceutical conditions by the respective brand marketing companies and their licensed manufacturers for regional distribution.
Related Products
Bismuth Subsalicylate
Strength:
262 mg, 525 mg
Form: Oral suspension / Tablet
Reference Brands: Pepto-Bismol (USA/LATAM),
View Details
Quick Response Guaranteed | Verified Suppliers
