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Lorlatinib bulk supplier for pharma manufacturers

Lorlatinib 25 mg, 50 mg,100 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 25 mg, 50 mg,100 mg

Reference Brands: Lorbrena (USA)

Category: Oncology Cancer Care

Lorlatinib is a Oncology Cancer Care product available as Tablets in strengths 25 mg, 50 mg,100 mg. It corresponds to the reference brand Lorbrena (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Lorlatinib, marketed under the brand names Lorbrena in the USA, Canada, and Japan, and Lorviqua in the European Union, is an oral anti-cancer medication used for the treatment of metastatic non-small cell lung cancer (NSCLC) in adults whose tumors are ALK-positive. As a targeted therapy, Lorlatinib works as an inhibitor of anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (ROS1), enzymes that are involved in cancer cell growth and proliferation. By blocking these kinases, Lorlatinib slows tumor progression and helps manage advanced lung cancer in patients who have developed resistance to prior ALK-targeted therapies.

Administered orally as a tablet, Lorlatinib is designed to provide systemic exposure to inhibit tumor activity while maintaining a manageable safety profile. It is particularly valuable for patients with metastatic NSCLC where standard chemotherapy and earlier-generation ALK inhibitors have failed. Lorlatinib has demonstrated efficacy in crossing the blood-brain barrier, addressing central nervous system metastases commonly observed in ALK-positive NSCLC. Approved in multiple regulated markets, Lorlatinib represents a critical treatment option for patients with advanced lung cancer, offering targeted therapy for improved clinical outcomes and disease management.

Lorlatinib — third party manufacturing & bulk supply

Lorlatinib 25 mg, 50 mg,100 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Lorlatinib listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Lorlatinib is used for the treatment of non-small cell lung cancer (NSCLC) in patients whose tumors have ALK-positive or ROS1-positive genetic mutations. It is particularly used in patients who have previously received other ALK-targeted therapies.

Lorlatinib is a synthetic tyrosine kinase inhibitor that selectively targets anaplastic lymphoma kinase (ALK) and ROS1 fusion proteins, blocking signaling pathways that promote cancer cell growth and survival.

The trade name of Lorlatinib is Lorbrena.

Lorbrena (Lorlatinib) is manufactured and marketed by Pfizer in the USA and other regulated markets.

The generic name is lorlatinib.

The brand name is Lorbrena.

Lorlatinib is manufactured in GMP-approved facilities by Pfizer in the USA, Europe, and other regulated markets, depending on regional approvals.

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