Pemigatinib 4.5 mg, 9 mg, 13.5 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 4.5 mg, 9 mg, 13.5 mg

Reference Brands: Pemazyre (USA/EU)

Category: Oncology Cancer Care

Pemigatinib tablets in 4.5 mg, 9 mg and 13.5 mg, an oral FGFR1-3 inhibitor for FGFR2-altered cholangiocarcinoma and FGFR1-rearranged neoplasms. For oncology pharmacies, hospitals and licensed importers.

Product Description:

Pemigatinib is a selective, reversible inhibitor of fibroblast growth factor receptors 1, 2 and 3. Some tumours carry FGFR gene fusions or rearrangements that keep the receptor permanently active, and blocking the kinase cuts off that growth signal. It is an oral tablet in three strengths, 4.5 mg, 9 mg and 13.5 mg. Having all three lets the prescriber step the dose down for side effects without splitting tablets, so a pharmacy usually stocks more than one.

Its main use is in adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with an FGFR2 fusion or rearrangement confirmed by a validated test. In the United States it is also approved for relapsed or refractory myeloid or lymphoid neoplasms with FGFR1 rearrangement. For bile duct cancer it is taken once daily for two weeks, then one week off; the haematological indication uses continuous dosing. High blood phosphate follows from the mechanism, so phosphate is checked and diet or binders adjusted. Serous retinal detachment calls for eye examinations. Strong CYP3A inhibitors and inducers are avoided.

Sourcing notes. Registration varies by market, and the indication depends on a molecular test, so oncology centres often arrange FGFR testing alongside supply. No cold chain is needed; tablets are kept at room temperature in the original pack. State which strengths and pack counts you need. For a registered product ask for the CoA per batch, GMP certificate and CoPP; for unregistered use, the named-patient import authorisation and a traceable source. It is a prescription-only oncology medicine supplied in original serialised packs.