Porfimer Sodium 75 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 75 mg

Reference Brands: Photofrin (USA/EU)

Category: Oncology Cancer Care

Porfimer Sodium is a Oncology Cancer Care product available as Injection in strengths 75 mg. It corresponds to the reference brand Photofrin (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Porfimer sodium, marketed under the brand name Photofrin, is a photosensitizing agent used in photodynamic therapy (PDT) and radiation therapy for the treatment of certain cancers. It is a sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units. Porfimer is selectively absorbed by tumor cells, where it becomes activated upon exposure to a red light source emitting at 630 nm. Activation produces reactive oxygen species, resulting in cytotoxicity that destroys malignant cells.

In addition to direct tumor cell death, Porfimer may induce ischemic necrosis secondary to vascular occlusion, partially mediated by the release of thromboxane A2. Clinically, it is indicated for the palliative treatment of obstructing endobronchial non-small cell lung carcinoma and obstructing esophageal cancer. The targeted photodynamic mechanism allows Porfimer to minimize damage to surrounding healthy tissue while providing effective tumor control.

Administered as a lyophilized powder for intravenous injection, Porfimer sodium represents a specialized approach to cancer therapy, offering clinicians a tool for both tumor ablation and palliation in patients with advanced or obstructive malignancies. Its unique photodynamic properties make it a valuable addition to oncology treatment regimens.