Efavirenz bulk supplier for pharma manufacturers

Efavirenz Suppliers & Bulk Manufacturers

Available Forms: Tablet & Capsule

Available Strengths: Tab: 200 mg, 600 mg; Cap: 50 mg, 100 mg, 200 mg

Reference Brands: Sustiva®(US); Stocrin®(EU)

Efavirenz 200 mg and 600 mg tablets and 50 mg, 100 mg and 200 mg capsules, an NNRTI antiretroviral for HIV-1, for national HIV programmes, tender buyers, hospitals and distributors.

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Product Description:

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) active against HIV-1 but not HIV-2. It binds the viral reverse transcriptase and stops it copying viral RNA into DNA. This page lists film-coated tablets at 200 mg and 600 mg and hard capsules at 50 mg, 100 mg and 200 mg. The 600 mg tablet is the adult once-daily dose; smaller strengths allow weight-band dosing in children, and some labels let the capsule be opened onto soft food.

Efavirenz is always combined with other antiretrovirals, often in a fixed-dose tablet with tenofovir and lamivudine or emtricitabine. WHO now prefers dolutegravir-based first-line regimens, and efavirenz has become an alternative option, with a 400 mg dose in some combinations. It is taken on an empty stomach at bedtime, as food raises levels and night dosing eases dizziness and vivid dreams. Psychiatric symptoms, rash, liver enzyme rises and QT prolongation are key precautions, and CYP2B6 and CYP3A4 interactions are many.

Sourcing notes. Efavirenz is a prescription-only antiretroviral bought mainly by national HIV programmes and donor-funded tenders, which usually require WHO prequalification or stringent regulator approval plus a CTD dossier with bioequivalence data. As demand shifts towards dolutegravir regimens, check your strength is still on the tender list before ordering. HDPE bottles, sometimes with desiccant, are typical; ask for stability data at zone IVb conditions. Request a batch CoA, GMP certificate and CoPP. Specify strength, tablet or capsule, count per bottle and labelling language.

Efavirenz — third party manufacturing & bulk supply

Efavirenz is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Efavirenz is supplied as Tablet & Capsule — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Efavirenz listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Efavirenz is used to treat HIV-1 infection. It helps reduce viral load and improve immune function by blocking the HIV reverse transcriptase enzyme. It is typically used as part of combination antiretroviral therapy.

Efavirenz is made from the active non-nucleoside reverse transcriptase inhibitor (NNRTI) compound efavirenz, a synthetic benzoxazinone derivative.

The well-known trade name is Sustiva.

Sustiva is manufactured by Bristol-Myers Squibb (BMS). Many generic pharmaceutical companies worldwide also produce efavirenz.

The generic name is efavirenz.

The primary brand name is Sustiva.

Efavirenz is manufactured in approved facilities across the USA, Europe, and India, depending on whether it is the innovator brand or a generic version.