Desloratadine bulk supplier for pharma manufacturers

Desloratadine 0.5 mg / ml Suppliers & Bulk Manufacturers

Available Forms: Syrup

Available Strengths: 0.5 mg / ml

Reference Brands: Clarinex (USA), Aerius (EU)

Desloratadine belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms like itching, swelling and rashes.

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Product Description:

Desloratadine is the principal active metabolite of loratadine, and this relationship explains its clinical positioning. Because it is already the active moiety, it does not depend on hepatic conversion, which gives a more consistent effect across patients with differing metabolic capacity. It is a second-generation antihistamine with high H1 selectivity and poor penetration of the blood-brain barrier, so sedation is uncommon at therapeutic doses.

The syrup presentation matters commercially out of proportion to its share of prescriptions. Paediatric allergic rhinitis and chronic urticaria are high-volume indications in emerging markets, and liquid presentations dominate where paediatric dosing by weight is the norm. A syrup at 0.5 mg per mL is the common international strength.

Sourcing notes. Desloratadine is off-patent and widely manufactured, so dossiers are readily available and competition is genuine — which makes plant approval, not price, the meaningful differentiator. Syrup manufacture requires liquid orals capability and, for export, a stability package covering the destination market's climatic zone. Zone IVb stability data is frequently the limiting factor for shipments into South and Southeast Asia and much of Africa, and it is worth confirming exists before a registration timeline is agreed.

Desloratadine — third party manufacturing & bulk supply

Desloratadine 0.5 mg / ml is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Desloratadine is supplied as Syrup — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Desloratadine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Desloratadine is used to relieve symptoms of allergic conditions such as hay fever (allergic rhinitis), urticaria (hives), sneezing, runny nose, and itchy or watery eyes. It is a long-acting antihistamine that works by blocking histamine, a natural substance in the body that causes allergy symptoms. Unlike some older antihistamines, desloratadine causes minimal drowsiness.

Desloratadine is made from the active ingredient desloratadine, which is the major active metabolite of loratadine. Its chemical name is 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine. It may also contain inactive ingredients such as lactose monohydrate, microcrystalline cellulose, and magnesium stearate depending on the dosage form.

The most common trade name of desloratadine is Clarinex in the United States and Aerius in the European Union and other regions.

Desloratadine (Clarinex/Aerius) is manufactured by Merck & Co., Inc. and marketed globally under various brand names by its subsidiaries and licensed partners.

The generic name of the drug is desloratadine.

The brand names of desloratadine include Clarinex and Aerius.

Desloratadine is manufactured in the United States and Europe by Merck & Co., Inc., and also in India and other regions by several generic manufacturers such as Sun Pharma, Dr. Reddy’s Laboratories, and Cipla for global distribution.