Clocortolone Pivalate 0.1% Suppliers & Bulk Manufacturers

Available Forms: Creams

Available Strengths: 0.1%

Reference Brands: Cloderm (USA)

Category: Derma Drugs

Clocortolone pivalate is a medium-potency topical corticosteroid used to relieve inflammation and itching associated with skin conditions such as eczema, dermatitis, psoriasis, and allergic rashes. It works by reducing the release of inflammatory substances in the skin.

Product Description:

Clocortolone pivalate is a medium-potency topical corticosteroid. Its distinguishing feature is chemical: it is a chlorinated steroid without the fluorine atoms that most potent topical steroids carry. Fluorination increases potency but also increases the risk of skin atrophy, telangiectasia and perioral dermatitis, so a non-fluorinated steroid at medium potency is positioned as a reasonable compromise for sites where a stronger agent would cause damage.

It is used for inflammatory and itchy dermatoses — eczema, contact dermatitis, seborrhoeic dermatitis — including on the face and in flexures, where dermatologists are cautious with fluorinated products. It is applied thinly up to three times daily. The usual topical steroid cautions still apply: atrophy and striae with prolonged use, particularly under occlusion, and enough absorption from large areas to matter in children. It should not be applied to untreated skin infection.

Sourcing notes. Essentially a US product — registration elsewhere is limited, so buyers outside the US will usually be looking at a locally registered medium-potency alternative such as clobetasone butyrate or hydrocortisone butyrate. Cream is the only common presentation. Confirm registration before pursuing supply.