Daxibotulinumtoxina-Lanm Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 50U, 100U

Reference Brands: Daxxify(USA)

Category: Derma Drugs

DaxibotulinumtoxinA-lanm is a neuromodulator derived from botulinum toxin type A, designed for injection to temporarily reduce muscle activity. It is approved for the improvement of moderate to severe glabellar (frown) lines in adults, and for the treatment of cervical dystonia in adult patients. Its unique peptide-stabilized formulation allows for longer duration of effect compared to traditional neuromodulators—clinical trials show effect lasting ~6 months and in some up to 9 months.

Product Description:

DaxibotulinumtoxinA-lanm is an advanced botulinum toxin type A formulation designed for aesthetic applications requiring prolonged neuromuscular blockade. Marketed as Daxxify by Revance Therapeutics, it is specifically approved for the treatment of moderate to severe glabellar lines (frown lines) in adults. Derived from Clostridium botulinum, this neurotoxin works by inhibiting the release of acetylcholine at the neuromuscular junction, resulting in temporary muscle relaxation and visible reduction in dynamic facial wrinkles.

What differentiates DaxibotulinumtoxinA-lanm from conventional botulinum toxin products is its unique formulation. It contains a highly purified 150-kDa botulinum toxin along with a proprietary stabilizing peptide (RTP004), eliminating the need for human serum albumin. This innovation contributes to its extended duration of action. Clinical studies have demonstrated a median effect duration of approximately 6 months, with some patients experiencing results lasting up to 9 months, significantly reducing the frequency of repeat treatments.

With its long-lasting efficacy, consistent performance, and favorable safety profile, DaxibotulinumtoxinA-lanm represents a next-generation neuromodulator, offering enhanced convenience and improved patient satisfaction in aesthetic practice.