Calcipotriene Suppliers & Bulk Manufacturers

Available Forms: Cream / Ointment / Gel

Available Strengths: 0.005% w/w

Reference Brands: Daivonex (EU), Dovonex (USA/EU)

Category: Derma Drugs

Product Description:

Calcipotriene (Calcipotriol) is a synthetic vitamin D3 derivative formulated for topical dermatological use, primarily in the treatment of plaque psoriasis. It acts by binding to vitamin D receptors in the skin, competing with the active form of vitamin D (1,25-dihydroxyvitamin D3), to regulate cell proliferation and differentiation. This targeted action induces keratinocyte differentiation while suppressing abnormal proliferation, helping to reverse the pathological changes seen in psoriatic lesions and promoting normalization of epidermal growth.

Calcipotriene is commonly used as a monotherapy or in combination with topical corticosteroids to enhance efficacy and improve treatment outcomes. It is available in various topical forms including cream, ointment, solution, gel, and foam, providing flexibility for different types and locations of psoriatic plaques. By restoring the balance of skin cell turnover, calcipotriene alleviates scaling, thickness, and redness associated with psoriasis.

Sold under brand names such as Dovonex, Daivonex, Sorilux, Taclonex, Daivobet, and Dovobet, calcipotriene is widely used across the USA, EU, and UK for effective, localized management of psoriasis with a favorable safety profile.