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Clindamycin / Tretinoin Gel bulk supplier for pharma manufacturers

Clindamycin / Tretinoin Gel Suppliers & Bulk Manufacturers

Available Forms: Gel

Available Strengths: 1.0% + 0.025% w/w, 1.0% + 0.05% w/w

Reference Brands: Ziana (USA/LATAM), Veltin (USA), Clindate-T (India)

Category: Derma Drugs

Clindamycin+Tretinoin is a combination of two medicines, used to treat acne, which appears as spots or pimples on your face, chest, or back. This medicine works by attacking the germs that cause them and rejuvenates sun-damaged skin. Clindamycin / Tretinoin Gel is available in Gel and strengths such as 1.0% + 0.025% w/w, 1.0% + 0.05% w/w. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Clindamycin / Tretinoin Gel is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Clindamycin / Tretinoin Gel can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Clindamycin phosphate 1.2% / tretinoin 0.025% gel is a topical combination therapy indicated for the treatment of acne vulgaris in patients aged 12 years and older. This once-daily formulation combines clindamycin, a lincosamide antibiotic that reduces acne-causing bacteria, with tretinoin, a retinoid that promotes skin cell turnover and prevents clogged pores. Together, they provide a dual mechanism of action that addresses both the microbial and follicular components of acne.

The efficacy and safety of this combination gel are well-established through extensive clinical studies. Three pivotal 12-week, randomized, vehicle-controlled trials involving over 1,800 subjects demonstrated significant improvement in inflammatory and non-inflammatory acne lesions. Additionally, an open-label 52-week study with 442 participants confirmed its long-term tolerability and skin safety. Pooled analyses from a total of 4,550 subjects further support the consistency of therapeutic outcomes.

Results from the Phase 3 studies in 845 subjects with mild to severe facial acne showed that the gel achieved clear or almost clear skin in a substantial proportion of patients, with many experiencing at least a 2-grade improvement in acne severity scores. Clindamycin phosphate 1.2% / tretinoin 0.025% gel is therefore a proven, effective, and safe once-daily option for managing acne vulgaris.

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Frequently Asked Questions

Clindamycin / Tretinoin gel is used for the topical treatment of acne vulgaris, particularly in patients with inflammatory and non-inflammatory acne lesions. The combination helps reduce acne-causing bacteria, inflammation, and clogged pores. It is commonly prescribed to manage mild to moderate acne and helps improve skin texture by reducing pimples, blackheads, and whiteheads.

Clindamycin / Tretinoin gel contains two active ingredients: clindamycin phosphate and tretinoin. Clindamycin phosphate is a lincosamide antibiotic that helps control the growth of acne-causing bacteria, while tretinoin is a retinoid derived from vitamin A that promotes skin cell turnover and prevents the formation of blocked pores.

Clindamycin / Tretinoin gel is marketed under several trade names worldwide, including Ziana Gel, Veltin Gel, and other generic combination acne treatment brands depending on the manufacturer and region.

One of the well-known brands, Ziana Gel, was developed and marketed by Bausch Health. Other companies also manufacture this combination gel in different regions as generic dermatology formulations.

The generic name is clindamycin phosphate and tretinoin gel.

Common brand names include Ziana Gel and Veltin Gel.

Clindamycin / Tretinoin gel is manufactured in several countries including the United States, India, and multiple European countries by different pharmaceutical manufacturers producing branded and generic dermatology products for global markets.

Yes, Clindamycin / Tretinoin Gel is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Clindamycin / Tretinoin Gel is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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