Clindamycin / Tretinoin Gel bulk supplier for pharma manufacturers

Clindamycin / Tretinoin Gel Suppliers & Bulk Manufacturers

Available Forms: Gel

Available Strengths: 1.0% + 0.025% w/w, 1.0% + 0.05% w/w

Reference Brands: Ziana (USA/LATAM), Veltin (USA)

Clindamycin 1% with tretinoin 0.025% or 0.05% gel, a once-daily antibiotic and retinoid combination for acne vulgaris, for importers, distributors, pharmacy wholesalers and dermatology buyers.

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Product Description:

This aqueous gel combines clindamycin, a lincosamide antibiotic, with tretinoin, a retinoid. Clindamycin reduces Cutibacterium acnes and the inflammation it drives, while tretinoin normalises shedding of follicle lining cells, clears comedones and stops new microcomedones forming. One gel treats inflammatory and non-inflammatory lesions with a single evening application, which helps adherence. The listed strengths give clindamycin 1% (as phosphate 1.2%) with tretinoin 0.025% or 0.05%; the 0.025% version matches the main reference products.

It is indicated for acne vulgaris from age 12. A pea-sized amount is spread over the affected face at bedtime after gentle washing, away from eyes, lips and mucous membranes. Dryness, peeling and redness are common early on. Tretinoin increases sun sensitivity, so sunscreen is advised, and it is avoided in pregnancy. Clindamycin is not used after inflammatory bowel disease or antibiotic-associated colitis, and is not combined with topical erythromycin. Abrasive cleansers and other drying products add to irritation.

Sourcing notes. Confirm which tretinoin strength is registered locally; the 0.05% combination is authorised only in some markets. Expect a CTD or ACTD dossier with stability for your climatic zone, including zone IVb for hot humid markets, because tretinoin degrades with light and heat. Keep at controlled room temperature, away from light, and do not freeze. Laminated or aluminium tubes are usual. Ask for a CoA per batch with assay of both actives, tretinoin degradation products, viscosity, pH and microbial limits, plus the GMP certificate and a CoPP. It is prescription-only.

Clindamycin / Tretinoin Gel — third party manufacturing & bulk supply

Clindamycin / Tretinoin Gel is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Clindamycin / Tretinoin Gel is supplied as Gel — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Clindamycin / Tretinoin Gel listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Clindamycin / Tretinoin gel is used for the topical treatment of acne vulgaris, particularly in patients with inflammatory and non-inflammatory acne lesions. The combination helps reduce acne-causing bacteria, inflammation, and clogged pores. It is commonly prescribed to manage mild to moderate acne and helps improve skin texture by reducing pimples, blackheads, and whiteheads.

Clindamycin / Tretinoin gel contains two active ingredients: clindamycin phosphate and tretinoin. Clindamycin phosphate is a lincosamide antibiotic that helps control the growth of acne-causing bacteria, while tretinoin is a retinoid derived from vitamin A that promotes skin cell turnover and prevents the formation of blocked pores.

Clindamycin / Tretinoin gel is marketed under several trade names worldwide, including Ziana Gel, Veltin Gel, and other generic combination acne treatment brands depending on the manufacturer and region.

One of the well-known brands, Ziana Gel, was developed and marketed by Bausch Health. Other companies also manufacture this combination gel in different regions as generic dermatology formulations.

The generic name is clindamycin phosphate and tretinoin gel.

Common brand names include Ziana Gel and Veltin Gel.

Clindamycin / Tretinoin gel is manufactured in several countries including the United States, India, and multiple European countries by different pharmaceutical manufacturers producing branded and generic dermatology products for global markets.