Fluocinolone Acetonide 0.025%, 0.01% Suppliers & Bulk Manufacturers

Available Forms: Topical cream/ ointment / lotion / gel

Available Strengths: 0.025%, 0.01%

Reference Brands: Synalar (USA/EU), Capex (USA/EU)

Category: Derma Drugs

Fluocinolone Acetonide is a Derma Drugs product available as Topical cream/ ointment / lotion / gel in strengths 0.025%, 0.01%. It corresponds to the reference brands Synalar (USA/EU), Capex (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Fluocinolone acetonide is a synthetic fluorinated corticosteroid widely used in dermatology and ophthalmology for its potent anti-inflammatory properties. As a hydrocortisone derivative, the fluorine substitution at position 9 of its steroid nucleus significantly enhances its activity, making it effective in reducing skin inflammation and relieving itching. It was first synthesized in 1959 by Syntex Laboratories, Mexico, and has been marketed under the brand name Synalar for topical dermatological applications.

Topically, fluocinolone acetonide is used to treat a variety of corticosteroid-responsive dermatoses, including eczema, psoriasis, and dermatitis, in forms such as creams, ointments, lotions, gels, and shampoos. Beyond dermatology, it has demonstrated strong potentiation of TGF-β-associated chondrogenesis in bone marrow mesenchymal stem/progenitor cells, increasing collagen type II production significantly, which is of interest in regenerative medicine research.

In ophthalmology, fluocinolone acetonide is formulated as intravitreal implants, such as Iluvien, to manage non-infectious uveitis and diabetic macular edema. These implants provide sustained corticosteroid delivery directly to the eye, reducing inflammation and supporting improved visual outcomes. Fluocinolone acetonide offers versatile applications across multiple specialties due to its potent anti-inflammatory and immunomodulatory effects.