Aripiprazole Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets/ODT

Available Strengths: 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg

Reference Brands: Abilify(EU & US)

Category: Antipsychotropic Drugs

Aripiprazole tablets and orodispersible tablets in 2 mg to 30 mg, an atypical antipsychotic for schizophrenia and bipolar disorder. For distributors, hospital and psychiatric pharmacies and tender buyers.

Product Description:

Aripiprazole is a second-generation antipsychotic. It is a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and an antagonist at 5-HT2A, so it steadies dopamine signalling rather than simply blocking it. This page covers 2, 5, 10, 15, 20 and 30 mg conventional tablets and orodispersible tablets (ODT). The ODT dissolves on the tongue without water, which helps patients who struggle to swallow and lets ward staff see that a dose has really been taken.

Main uses are schizophrenia and bipolar I disorder, for mania and for maintenance. Some labels add adjunctive use in major depression, irritability with autism and Tourette's disorder, so indications differ by market. It is taken once daily with or without food, and steady state takes about two weeks. Doses are cut with strong CYP2D6 or CYP3A4 inhibitors and raised with inducers such as carbamazepine. Prescribers watch for akathisia, impulse-control problems and increased mortality in elderly patients with dementia.

Sourcing notes. Aripiprazole is prescription-only and widely registered on a bioequivalence dossier in CTD or ACTD format. Treat tablets and ODT as separate products, each with its own dossier and stability data. ODTs are soft and moisture sensitive, so they usually come in peel-push or alu-alu blisters, and many contain aspartame, which must be declared for phenylketonuria. Request the excipient list and Zone IVb data for humid markets. Each batch should carry a certificate of analysis, backed by a site GMP certificate and a CoPP. State form, strengths, pack size and labelling language when you enquire.