Alfentanil 500 mcg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 500 mcg/mL

Reference Brands: Alfenta (USA), Rapifen (EU)

Category: Analgesic

Alfentanil is a short-acting opioid analgesic used in anesthesia and surgical procedures for rapid pain relief and sedation. With a very fast onset and short duration, it is ideal for short surgical interventions.

Product Description:

Alfentanil is a synthetic opioid of the fentanyl family, designed for speed. It is less lipid-soluble than fentanyl but largely un-ionised at blood pH, so it crosses into the brain very quickly: peak effect arrives in about ninety seconds, against several minutes for fentanyl. Its small volume of distribution gives it a short duration, so it can be titrated closely to brief, intense stimuli.

It is used in anaesthesia — for intubation, short procedures, and as an infusion during surgery — and in intensive care for procedural pain. Its profile suits exactly the situations where an opioid is needed for minutes rather than hours. Like all potent opioids it causes dose-dependent respiratory depression, and it must only be used where airway management and reversal agents are immediately available. Chest wall rigidity can occur with rapid injection of high doses. Its effect is prolonged by liver impairment and by CYP3A4 inhibitors such as erythromycin.

Sourcing notes. Alfentanil is a Schedule I narcotic under the 1961 UN Single Convention. Every consignment needs an import authorisation from the destination country and an export authorisation from the source, within national quotas, with secure storage and full accountability at each step. Hospital and anaesthesia demand only.

Controlled medicine — licensed supply only

This product is controlled in many countries under narcotic, psychotropic, precursor or other drug laws, which vary by country. We supply only licensed buyers holding any import certificate, permit or authorisation their national authority requires, and the Indian manufacturer or exporter must hold the required licences. In India, each export of a narcotic drug or psychotropic substance needs an export authorisation, and export of ephedrine, pseudoephedrine or their preparations a No Objection Certificate, from the Narcotics Commissioner (Central Bureau of Narcotics). We verify permits before quoting.