Dexketoprofen + Tramadol tablets bulk supplier for pharma manufacturers

Dexketoprofen + Tramadol Tablets Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 25 mg dexketoprofen + 37.5 mg tramadol

Reference Brands: Enantyum(EU)

Category: Analgesic

Dexketoprofen + Tramadol combines dexketoprofen’s inhibition of COX enzymes, reducing prostaglandin synthesis, with tramadol’s activation of opioid receptors and serotonin/norepinephrine reuptake inhibition. Benefits include effective relief from moderate to severe acute pain, rapid onset, and dual mechanisms for enhanced analgesia, with manageable side effects when used responsibly.

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Product Description:

Dexketoprofen + Tramadol tablets are approved in the EU for managing moderate to severe acute pain, supported by dossiers demonstrating safety, efficacy, and manufacturing standards. In the US, this combination is currently not approved or marketed. In the EU, regulatory approval requires comprehensive clinical data and pharmacovigilance plans. Both regions enforce strict prescribing regulations due to the opioid component. For expert assistance with regulatory dossiers, compliance, and registration, visit PharmaTradz. We facilitate seamless market access for dexketoprofen + tramadol formulations, ensuring adherence to European standards for safe, effective analgesic therapy while navigating complex regulatory pathways effectively.

Dexketoprofen + Tramadol Tablets — third party manufacturing & bulk supply

Dexketoprofen + Tramadol Tablets is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Dexketoprofen + Tramadol Tablets is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Dexketoprofen + Tramadol Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Dexketoprofen + tramadol is used for short-term treatment of moderate to severe acute pain when a single analgesic is not enough. It is commonly prescribed for postoperative pain, musculoskeletal pain, trauma-related pain, dental pain, and painful inflammatory conditions. The combination offers both fast onset of action and stronger pain control.

This combination contains two active ingredients: dexketoprofen trometamol, a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain, and tramadol hydrochloride, an opioid analgesic that acts on the central nervous system to block pain signals. Together, they provide dual analgesic action.

Common trade names include Skudexa, Tramix, and other region-specific brands. The availability of each brand varies by country.

Skudexa, one of the widely known brands, is manufactured by Menarini. Other pharmaceutical companies also produce the combination for global markets under different brand names.

The generic name is dexketoprofen trometamol and tramadol hydrochloride combination.

Brand names include Skudexa, Tramix, and several regional equivalents depending on the market.

This combination is manufactured in various regions including Europe, Asia, and Latin America, with availability depending on country-specific regulatory approvals.